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FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response.

Xie(Jenny),Peng(Min),Guillemette(Shawna),Qua… PLoS Genet 2012-09-25

BRCA1 promotes DNA repair through interactions with multiple proteins, including CtIP and FANCJ (also known as BRIP1/BAC...

The CRM1 nuclear export protein in normal development and disease.

Nguyen(Kevin T),Holloway(Michael P),Altura(R… Int J Biochem Mol Biol 2012-10-02

...BRCA1, Survivin, NPM, and APC, which function in the nucleus to regulate transcription or aid in chromosomal assembly an...

A distinct replication fork protection pathway connects Fanconi anemia tumor su…

Schlacher(Katharina),Wu(Hong),Jasin(Maria) Cancer Cell 2012-09-17

Genes mutated in patients with Fanconi anemia (FA) interact with the DNA repair genes BRCA1 and BRCA2/FANCD1 to suppress...

Prediction of BRCA1 germline mutation status in women with ovarian cancer using…

Fujiwara(Mika),McGuire(Valerie A),Felberg(An… Am J Surg Pathol 2012-09-18

...BRCA1 status: "Compatible with BRCA1," "Possibly compatible with BRCA1," and "Not compatible with BRCA1." All "Compatibl...

Amplified detection of DNA through the enzyme-free autonomous assembly of hemin…

Shimron(Simcha),Wang(Fuan),Orbach(Ron),Willn… Anal Chem 2012-05-15

...BRCA1 oncogene with a detection limit of 1 × 10(-13) M.

Long-term follow-up of Jewish women with a BRCA1 and BRCA2 mutation who underwe…

Metcalfe(Kelly A),Mian(Nida),Enmore(Melissa)… Breast Cancer Res Treat 2012-09-28

...BRCA1 and one in BRCA2, which are present in up to 2.5% of Jewish women. Population genetic testing for Jewish women has...

BRCA1/2 carriers: their childbearing plans and theoretical intentions about hav…

Julian-Reynier(Claire),Fabre(Roxane),Coupier… Genet Med 2012-08-30

To assess the impact of BRCA1/2 test results on carriers' reproductive decision-making and the factors determining their...

Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombi…

Pan(Mei-Ren),Hsieh(Hui-Ju),Dai(Hui),Hung(Wen… J Biol Chem 2012-04-25

...BRCA1 C-terminal domains of BRIT1 are required for its interaction with CHD4. Depletion of CHD4 and overexpression of th...

Genetics of breast cancer: applications to the Mexican population.

Ziv(Elad) Salud Publica Mex 2012-05-08

...BRCA1 and BRCA2 and more recently 19 genes and genetic loci that confer a more moderate risk.The pace of discovery is ac...

[Genetic predisposition for breast cancer: BRCA1 and BRCA2 genes].

Narod(Steven A),Rodríguez(Adriana A) Salud Publica Mex 2012-05-08

...BRCA1 and BRCA2 has led to the introduction of genetic tests more complex every time for the evaluation of the hereditar...

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