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TP53 BRCA1 CRISPR single-cell cancer

Shao(Zhenhua),Li(Fudong),Sy(Shirley M-H),Yan… J Struct Biol 2012-06-05

...BRCA1-carboxyl terminal) domains. The N-terminal region directly binds with chromatin remodeling complex SWI-SNF, and th...

Schneegans(S M),Rosenberger(A),Engel(U),Sand… Fam Cancer 2012-11-30

Many studies have evaluated the performance of risk assessment models for BRCA1/2 mutation carrier probabilities in diff...

Duquette(D),Lewis(K),McLosky(J),Bach(J) Public Health Genomics 2012-06-05

...BRCA1 or BRCA2 be referred for genetic counseling and evaluation for BRCA testing.,Through a cooperative agreement with ...

Busacca(Sara),Sheaff(Michael),Arthur(Kenneth… J Pathol 2012-06-22

...BRCA1 expression level; (2) induction of resistance to vinorelbine by BRCA1 using siRNA oligonucleotides; (3) dramatic d...

Shukla(Praphulla C),Singh(Krishna K),Quan(Ad… Nat Commun 2012-04-02

...BRCA1 as a gatekeeper of cardiac function and survival. In mice, loss of BRCA1 in cardiomyocytes results in adverse card...

Cardinale(F),Bruzzi(P),Bolognesi(C) Br J Cancer 2012-03-29

...BRCA1/2 mutation carriers. Our meta-analysis reveals a significant increase of baseline MN frequency related to cancer s...

Sidon(L),Ingham(S),Clancy(T),Clayton(R),Clar… Br J Cancer 2012-03-29

...BRCA1/2 mutation carriers from Greater Manchester.,Dates of last follow-up and BRRSO were obtained, and the following va...

Moran(A),O'Hara(C),Khan(S),Shack(L),Woodward… Fam Cancer 2012-11-30

The risks of cancers other than breast and ovarian amongst BRCA1 and BRCA2 mutation carriers are based on relatively few...

Abele(Andris),Vjaters(Egils),Irmejs(Arvīds),… Medicina (Kaunas) 2012-02-24

...BRCA1 gene for 112 prostate cancer patients with a history of breast or ovarian cancer in their families.,Of the 1217 fa...

Roy(Rohini),Chun(Jarin),Powell(Simon N) Nat Rev Cancer 2012-02-09

The proteins encoded by the two major breast cancer susceptibility genes, BRCA1 and BRCA2, work in a common pathway of g...

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