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TP53 BRCA1 CRISPR single-cell cancer

Soslow(Robert A),Han(Guangming),Park(Kay J),… Mod Pathol 2012-07-30

...BRCA1-associated cases (BRCA1 germline mutation, n=4, BRCA1 somatic mutation, n=6, BRCA1 promoter methylation, n=13) wit...

Kang(Hyo Jin),Hong(Young Bin),Kim(Hee Jeong)… Toxicol Lett 2012-06-04

...BRCA1 compared to the control. Overexpression of Nrf2 in BRCA1 deficient cells reduced elevated ROS to the control level...

Okada(Satoko),Tokunaga(Eriko),Kitao(Hiroyuki… Ann Surg Oncol 2012-08-16

...BRCA1 and BRCA2 loci, 69 (41.6%) and 52 (31.3%) tumors revealed LOH at BRCA1 and BRCA2 loci, respectively. LOH at BRCA1 ...

Ng(Charlotte K Y),Cooke(Susanna L),Howe(Kevi… J Pathol 2012-04-27

...BRCA1/2 carrier mutations.

Ewald(Ingrid P),Izetti(Patrícia),Vargas(Fern… Hered Cancer Clin Pract 2012-10-02

...BRCA1 c.68_69del and BRCA2 c.5946del is not justified, and that screening for BRCA1c.5266dup should be considered in hig...

Ramón Y Cajal(Teresa),Polo(Ana),Martínez(Olg… Fam Cancer 2012-11-30

Carriers of a mutation in BRCA1/2 genes confront a high lifetime risk of breast and ovarian cancer and fifty percent pro...

Bijron(Jonathan G),van der Groep(Petra),van … Endocr Relat Cancer 2012-06-14

BRCA1/2 germ line mutation carriers have a high risk of developing fallopian tube carcinoma (FTC), thought to occur thro...

Smith(Karen Lisa),Isaacs(Claudine) Cancer J 2012-06-18

...BRCA1 and BRCA2 mutations is available at the time of breast cancer diagnosis, BRCA mutation status can be considered wh...

Patel(Ketan J),Crossan(Gerry P),Hodskinson(M… Cancer Cell 2012-02-06

BRCA1 is a crucial human breast and ovarian cancer tumor suppressor gene. The article by Drost et al. in this issue of C...

Drost(Rinske),Bouwman(Peter),Rottenberg(Sven… Cancer Cell 2012-02-06

...BRCA1 mutations. The BRCA1(C61G) mutation in the BRCA1 RING domain is a common pathogenic missense variant, which reduce...

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