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Breast cancer prognosis in BRCA1 and BRCA2 mutation carriers: an International …

Goodwin(Pamela J),Phillips(Kelly-Anne),West(… J Clin Oncol 2012-02-13

To compare breast cancer prognosis in BRCA1 and BRCA2 mutation carriers with that in patients with sporadic disease.,An ...

Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302.

Meng(Fanying),Evans(James W),Bhupathi(Deepth… Mol Cancer Ther 2012-07-09

...BRCA1, BRCA2, and FANCA. Finally, we characterized TH-302 activity in the three-dimensional tumor spheroid and multicell...

[EGFR gene copy number, ERCC1 and BRCA1 protein expression and their relationsh…

Deng(Qiu-hua),Qiu(Yuan),Mo(Ming-cong),Zhang(… Zhonghua Zhong Liu Za Zhi 2012-06-14

...BRCA1 protein was identified in 46 of 131 samples (35.1%). The expression of BRCA1 was not associated with age gender, p...

The introduction of a choice to learn pre-symptomatic DNA test results for BRCA…

Voorwinden(J S),Jaspers(J P C),ter Beest(J G… Clin Genet 2012-08-07

...BRCA1/2 or Lynch syndrome mutation were randomised into two groups. The control group was given the DNA test result in a...

Breast cancer patients with hypermethylation in the promoter of BRCA1 gene exhi…

Krasteva(M E),Bozhanov(S S),Antov(G G),Gospo… Neoplasma 2012-07-12

...BRCA1 hypermethylation in sporadic breast cancer to identify a specific molecular and clinico-pathological phenotype. Ho...

Predictive value of MGMT, hMLH1, hMSH2 and BRCA1 protein expression for patholo…

Nakai(Katsuya),Mitomi(Hiroyuki),Alkam(Yimit)… Cancer Chemother Pharmacol 2012-07-27

...BRCA1 before and after NACT were evaluated.,A pCR was obtained in 10 of 32 cases (31%). Cancer-related (P = 0.013) and d...

Parenting through genetic uncertainty: themes in the disclosure of breast cance…

Sharff(McKane E),DeMarco(Tiffani A),Mays(Dar… Genet Test Mol Biomarkers 2012-10-10

...BRCA1/2 testing and their spouses/partners, this study sought to examine decision support needs and motivations for fami...

Regulating the levels of key factors in cell cycle and DNA repair: new pathways…

Redwood(Abena B),Gonzalez-Suarez(Ignacio),Go… Cell Cycle 2012-08-28

...BRCA1 and RAD51--exert tumor suppressor functions, with their loss being associated with cancer susceptibility. Moreover...

Filamin-A as a marker and target for DNA damage based cancer therapy.

Yue(Jingyin),Lu(Huimei),Liu(Jingmei),Berwick… DNA Repair (Amst) 2012-05-18

...BRCA1 and BRCA2. Defects of filamin-A impair the repair of DNA double strand breaks (DSBs), resulting in sensitization o...

Aberrant expression of miR-638 contributes to benzo(a)pyrene-induced human cell…

Li(Daochuan),Wang(Qing),Liu(Caixia),Duan(Hua… Toxicol Sci 2012-05-17

...BRCA1), one of the target genes of miR-638. In summary, we suggest that miR-638 is involved in the BaP-induced carcinoge...

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