...BRCA1/2 mutation, of whom 380 had no previous cancer history, were enrolled in a prospective screening trial that includ...
...BRCA1 and BRCA2. Our findings provide strong circumstantial evidence to suggest that acral melanoma cell lines and acral...
...BRCA1 binding domain is important in cancer predisposition.,Germline BAP1 mutations are associated with a more aggressiv...
...BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expres...
...BRCA1-associated ring domain) was originally identified as a BRCA1-interacting protein but has also been described in tu...
...BRCA1/2-related breast cancers, genomic profiling now shows that there is incomplete overlap, with important distinction...
...BRCA1/2-negative families with family histories of both ovarian and breast cancer ascertained from two Canadian and two ...
...BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectiveness of PARP inhibitors in targeting at...
...Brca1(-/-); p53(-/-) mouse model of hereditary breast cancer that develops sporadic tumors similar to cancers in women h...
...BRCA1/2, but have frequent mutations of Ras and Raf as well as expression of IGFR and activation of the phosphatidylinos...
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