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Predictive markers in the adjuvant therapy of non-small cell lung cancer.

Filipits(Martin),Pirker(Robert) Lung Cancer 2012-03-06

...BRCA1, EGFR, or gene signatures have been characterized in retrospective analyses of adjuvant therapy trials. However, d...

Designed hybridization properties of DNA-gold nanoparticle conjugates for the u…

Oh(Ju-Hwan),Lee(Jae-Seung) Anal Chem 2012-01-30

...BRCA1 has been carefully designed and demonstrated.

Reduced level of ribonucleotide reductase R2 subunits increases dependence on h…

Lin(Z Ping),Lee(Yashang),Lin(Fang),Belcourt(… Mol Pharmacol 2012-01-12

...BRCA1, an important factor of homologous recombination repair (HRR), preferentially sensitized stable R2-knockdown p53(-...

[Transcriptomic regulation and molecular mechanism of polygenic tumor at differ…

Li(Xiayu),Shen(Shourong),Wu(Minghua),Li(Xiao… Zhong Nan Da Xue Xue Bao Yi X… 2012-09-06

...BRCA1/2, PALB2, AF1Q, SOX17, NGX6, SOX7, and LRRC4 have been identified as the key transcriptional regulation genes duri...

Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis.

Gorski(Julia J),Savage(Kienan I),Mulligan(Ju… Nucleic Acids Res 2012-02-07

...BRCA1 depletion results in transcriptional changes in 1294 genes, only 44 of these are promoter bound by BRCA1. However,...

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer …

Cox(David G),Simard(Jacques),Sinnett(Daniel)… Hum Mol Genet 2012-02-22

...BRCA1 gene would modify the risk of breast cancer in carriers of BRCA1 mutations. A total of 9874 BRCA1 mutation carrier...

Quality of life and health status after prophylactic salpingo-oophorectomy in w…

Finch(Amy),Narod(Steven A) Maturitas 2012-03-27

...BRCA1 or BRCA2 mutation at age 35 or after childbearing is complete. This procedure is the mainstay of ovarian and fallo...

Genomics and pharmacogenomics of breast cancer: current knowledge and trends.

Ayoub(Nehad),Lucas(Courtney),Kaddoumi(Amal) Asian Pac J Cancer Prev 2012-05-29

...BRCA1 and BRCA2 genes have been well-characterized to carry a high risk of the disease during a woman's lifespan. Howeve...

[Relationship between BRCA1 mRNA expression in tumor cells from malignant effus…

Qian(Xiao-ping),Liu(Bao-rui),Jiang(Min),Hu(J… Zhonghua Zhong Liu Za Zhi 2012-05-24

...BRCA1) in tumor cells isolated from malignant pleural and peritoneal effusions, and the predictive role of BRCA1 related...

Genetic risk prediction in complex disease.

Jostins(Luke),Barrett(Jeffrey C) Hum Mol Genet 2012-01-23

...BRCA1/2 in breast cancer). The advent of genome-wide association studies (GWAS) has led to the discovery of common risk ...

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