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Jurgiel(WA),Panasiuk(B),Posmyk(R) Discov Oncol 2026-01-15

...BRCA1/BRCA2 underlie the majority of hereditary ovarian cancers and belong to the group of genes with high penetrance wh...

Chawapun(P),Khamto(N),Halimi(YF),Utama(K),... Bioorg Chem 2026-03-00

...BRCA1, Caspase-3, CDKN1A, Mcl-1, and PIK3CA, potentially influencing apoptosis via the PI3K/AKT pathway. The compound 2j...

Sims(TT),Sood(AK),Westin(SN),Rangel(K),Fle... Int J Gynecol Cancer 2026-07-00

...BRCA1/BRCA2 mutation or have tumors characterized by homologous recombination deficiency (HRD). We hypothesized that ger...

Chen(M),Dong(Y),Wang(R),Cui(H) Ann Ital Chir 2026-02-09

...BRCA1) and breast cancer gene 2 (BRCA2) are core regulators of the DNA damage homologous recombination repair (HRR) path...

Cylwik(D),Dwornik(R),Białkowska(K) Cancers (Basel) 2026-01-23

...BRCA1 and BRCA2 genes, which are major contributors to hereditary susceptibility to this malignancy. Although PV carrier...

Kulikowska(B),Panasiuk(B),Posmyk(R) Cancers (Basel) 2026-02-02

...BRCA1 and BRCA2 genes are particularly notable, especially in certain populations where founder mutations (specific gene...

Durán-Maldonado(MX),Hernández-Ramos(X),Cam... Molecules 2026-02-04

...BRCA1, GADD45A, and PD-L1-were dysregulated in the livers of TNBC-bearing mice; however, CDP treatment restored their ex...

Kluk(A),Gryczka(H),Braszka(M),Ałtyn(R),Mar... Int J Mol Sci 2026-01-28

...BRCA1/2)-also contribute to hereditary endometrial cancer risk. Recognition of these genetic backgrounds is essential fo...

Aranda-Gutierrez(A),Villarreal-Garza(C),Ag... Patient Educ Couns 2026-06-00

...BRCA1 (36.8 %) and BRCA2 (25.7 %). The mean knowledge score was 9.42 out of 16 (SD 3.0), with item-level gaps most prono...

Sheela(IJ),Jeya Ranchani(AA),Murali(A),Pre... Clin Breast Cancer 2026-03-00

...BRCA1/2 mutation carriers, while therapeutic vaccines, particularly for triple-negative breast cancer, stimulate T-cell ...