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TP53 BRCA1 CRISPR single-cell cancer

Ibragimova(Ilsiya),Cairns(Paul) Methods Mol Biol 2012-01-05

...BRCA1 promoter hypermethylation show a similar phenotype to familial BRCA1 patient tumors termed "BRCAness." Sporadic ov...

Kothe(Gregory O) Methods Mol Biol 2012-01-05

...BRCA1/2-associated tumors, prompting Bruce Alberts to call for an expansion of cancer research beyond utilization of can...

Dick(Michelle G),Versmold(Beatrix),Engel(Chr… Int J Cancer 2012-06-01

...BRCA1 and BRCA2 mutations. The DR-4 haplotype 626C-683C [626C > G, Thr209Arg (rs4871857) and 683A > C, Glu228Ala (rs1708...

Han(Sang Ah),Park(Sue K),Ahn(Sei Hyun),Lee(M… Clin Oncol (R Coll Radiol) 2012-01-31

The primary aims of the Korean Hereditary Breast Cancer (KOHBRA) study are to estimate the prevalence of BRCA1/2 mutatio...

Lindeman(Geoffrey J),Visvader(Jane E) Breast Cancer Res 2012-05-25

Understanding why BRCA1 mutation carriers have a predilection for developing clinically aggressive basal-like breast tum...

Bernholtz(Shiri),Laitman(Yael),Kaufman(Bella… Breast Cancer Res Treat 2012-09-14

BRCA1 and BRCA2 germline mutations substantially increase breast and ovarian cancer risk, yet penetrance is incomplete. ...

Dhar(S U),Cooper(H P),Wang(T),Parks(B),Stagg… Breast Cancer Res Treat 2012-09-14

...BRCA1 mutation. For women negative for the BRCA1 mutation, 59% of the physicians recommended appropriate surveillance al...

Martrat(Griselda),Maxwell(Christopher M),Tom… Breast Cancer Res 2012-05-25

...BRCA1/2 mutations were analyzed for genetic mutations. Common genetic variants were genotyped in 9,573 BRCA1/2 mutation ...

Miyashita(Hitoshi),Mori(Shiro),Fukumoto(Yuta… Mol Med Rep 2012-10-02

...BRCA1, BRCA2 and DCC was 20.0% (2/10). These observations suggest that transformations in PTHR1 may be involved in carci...

Fiore(Mathieu),Pillois(Xavier),Nurden(Paquit… Eur J Hum Genet 2012-01-03

...BRCA1 and THRA genes at chromosome 17, using fragment analysis gels. We found that a haplotype of five polymorphic loci ...

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