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Spinophilin: a new tumor suppressor at 17q21.

Carnero(A) Curr Mol Med 2012-10-17

...BRCA1. Spn is located in this locus and proposed to be a new tumor suppressor. Loss of Spn induces a proliferative respo...

Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated m…

Wang(Lin),Huang(Juxiang),Jiang(Minghu),Lin(H… Immunol Res 2012-09-04

...BRCA1, CCL20, MCM2, MS4A2, NTN1, REG1A, TP53I11, VCAN, SLC16A3, etc. in no-tumor hepatitis/cirrh...

Collective evidence supports neutrality of BRCA1 V1687I, a novel sequence varia…

Cortesi(Laura),De Nicolo(Arcangela),Medici(V… Breast Cancer Res Treat 2012-11-19

...BRCA1/BRCA2 mutational screening, we identified a previously unreported BRCA1 sequence alteration [c.5178G>A (V1687I)] i...

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order ch…

Luijsterburg(Martijn S),Acs(Klara),Ackermann… EMBO J 2012-08-13

...BRCA1 at DNA double-strand breaks. Interestingly, RNF8-mediated recruitment of CHD4 and subsequent chromatin remodelling...

Toward a new understanding of risk perception among young female BRCA1/2 "previ…

Hoskins(Lindsey M),Roy(Kevin M),Greene(Mark … Fam Syst Health 2012-07-13

The quantitative risk of cancer among BRCA1/2 gene mutation carriers is generally well-understood, and can be communicat...

Accuracy of BRCA1/2 mutation prediction models in Korean breast cancer patients.

Kang(Eunyoung),Park(Sue K),Yang(Jae Jeong),P… Breast Cancer Res Treat 2012-12-13

BRCAPRO and Myriad II are widely used models for predicting BRCA1/2 mutation probability before genetic testing. However...

Hereditary breast cancer: practical pursuit for clinical translation.

Lynch(Henry T),Snyder(Carrie),Lynch(Jane) Ann Surg Oncol 2012-10-09

...BRCA1 and BRCA2 in hereditary breast-ovarian cancer syndrome and p53 in the Li-Fraumeni syndrome, and many other syndrom...

KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated…

Cerne(Jasmina-Ziva),Stegel(Vida),Gersak(Ksen… BMC Cancer 2012-07-17

...BRCA1/2 mutations) and 270 postmenopausal control women using the flurogenic 5' nuclease assay. Information on hormone r...

The role of BRCA1 and BRCA2 in prostate cancer.

Castro(Elena),Eeles(Rosalind) Asian J Androl 2012-09-20

...BRCA1 in prostate tumorigenesis remains unrevealed, deleterious mutations in both genes have been associated with more a...

Tandem duplication of chromosomal segments is common in ovarian and breast canc…

McBride(David J),Etemadmoghadam(Dariush),Coo… J Pathol 2012-09-25

...BRCA1 or BRCA2 mutation showed a high frequency of small chromosomal deletions. These findings indicate that BRCA1/2 ger...

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