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Combined analysis of mRNA expression of ERCC1, BAG-1, BRCA1, RRM1 and TUBB3 to …

Leng(Xue-Feng),Chen(Ming-Wu),Xian(Lei),Dai(L… J Exp Clin Cancer Res 2012-08-24

...BRCA1 negative expression might have a longer OS (P = 0.052), but not PFS (P = 0.088) than those with BRCA1 positive exp...

Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genoty…

Liu(Joyce),Cristea(Mihaela C),Frankel(Paul),… Cancer Genet 2012-05-07

...BRCA1 versus BRCA2 patients. We identified 197 cases (148 BRCA1 cases; 49 BRCA2 cases); the median follow-up period was ...

Development of a novel approach, the epigenome-based outlier approach, to ident…

Kikuyama(Mizuho),Takeshima(Hideyuki),Kinoshi… Cancer Lett 2012-08-20

...BRCA1, HOXA5, MLH1, and RASSF1A had high Pol II, but were expressed only at low levels in normal cells, and were unlikel...

Characterization of four novel BRCA2 large genomic rearrangements in Spanish br…

Ruiz de Garibay(Gorka),Gutiérrez-Enríquez(Sa… Breast Cancer Res Treat 2012-08-20

...BRCA1 and BRCA2 small genomic alterations (substitutions and indels) and BRCA1 LGRs. We used a combination of long-range...

Prevalence of BRCA1 mutations among 403 women with triple-negative breast cance…

Fostira(Florentia),Tsitlaidou(Marianthi),Pap… Breast Cancer Res Treat 2012-11-19

...BRCA1 pathway, there is a lack of population studies that determine the frequency of BRCA1 mutations among triple-negati...

Germline copy number variants are not associated with globally acquired copy nu…

Walker(Logan C),Krause(Lutz),,Spurdle(Amanda… Breast Cancer Res Treat 2012-12-13

...BRCA1 breast tumours are characterised by basal-like phenotype and high-histological grade which are typically associate...

What drives breast cancer heterogeneity: oncogenic events or cell of origin?

Ginestier(Christophe),Charafe-Jauffret(Emman… J Pathol 2012-08-13

...BRCA1 tumours, they suggest that genomic alterations are not sufficient to determine tumour behaviour. These and other r...

BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in br…

Shimizu(Yoshiko),Mullins(Nicole),Blanchard(Z… Oncotarget 2012-09-05

...BRCA1/p220 expression. Here we show that BRCA1/p220 silencing in normal human mammary epithelial (HME) cells reduces exp...

Translational advances regarding hereditary breast cancer syndromes.

Gage(M),Wattendorf(D),Henry(L R) J Surg Oncol 2012-05-08

...BRCA1 and BRCA2. A substantial minority are caused by non-BRCA mutations, such as TP53, PTEN, STK11, CHEK2, ATM, BRIP1, ...

Detection of BRCA1 and BRCA2 gene mutation in Egyptian females with breast canc…

Fattouh(Mona),Ahmed(Hydi),Hafez(Elsayed El-S… Egypt J Immunol 2012-11-13

...BRCA1 and BRCA2 genes. Five mutations were detected in 52 families (86.7%) with inherited mutations in either BRCA1 or B...

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