...BRCA1 and BRCA2, a significant fraction of tests results in the detection of a genetic variant for which disease associa...
...BRCA1 and BRCA2. The main inclusion criterion is that each variant should have been assessed in a published work that us...
Women with BRCA1/2 mutations have a significantly higher lifetime risk of developing breast or ovarian cancer. We sugges...
...BRCA1- and BRCA2-mutated tumours. We conclude that 11q13 includes many potential target genes in addition to CCND1.
BARD1 heterodimerizes with BRCA1, forming an E3 ubiquitin ligase that functions at nuclear foci to repair DNA damage and...
...BRCA1 and BRCA2 carriers is available. Data on appendectomy, cancer type, and age at diagnosis were collected from BRCA1...
BRCA1 carboxyl-terminal (BRCT) motifs are present in a number of proteins involved in DNA repair and/or DNA damage signa...
...BRCA1, FOXA1, POSTN, DICER1, LIG4, KLF4, NOTCH2, RIF1, BMPR1A, TGFB2). Pregnancy and lactation displayed distinct patter...
...BRCA1 germline mutation.,ACC is moderately chemoresponsive to agents that have activity in pancreatic adenocarcinoma and...
...BRCA1, and several tyrosine kinase activations has been shown in this specific phenotype. An optimal chemotherapy regime...
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