...BRCA1/BRCA2 mutations require individualized counseling for informed decision-making, with benefits weighed against the ...
...BRCA1 and/or BRCA2 mutations. Other molecular characteristics are important in distinct types of EOC, but the use of mat...
...BRCA1/BRCA2-containing complex subunit 3] isopeptidase complex), a K63-specific deubiquitinase, in hypertensive cardiac ...
...BRCA1/2 alterations, whereas outcomes among patients with non- BRCA defective homologous recombination repair (HRR) gene...
...BRCA1/2 alterations. Sensitivity analyses confirmed the robustness of the KRAS finding. Study heterogeneity was moderate...
...BRCA1/2, cfDNA has shown value for detecting minimal residual disease, informing targeted therapy selection (eg, PARP in...
...Brca1⁻/⁻p53⁻/⁻ organoid-derived TNBC model that recapitulates the immune landscapes of basal-like tumours, we show that ...
...BRCA1 and RAD51AP1 promoter regions that would otherwise suppress transcription. In vivo, TRIB3 silencing suppresses HCC...
...BRCA1 or BRCA2 mutation are frequently advised to undergo risk-reducing bilateral salpingo-oophorectomy (BSO) to lower t...
...BRCA1, POLE, ATM and FANCA in 18/173 (10.40%) of patients, and presence of two or more mutations in these genes was asso...
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