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TP53 BRCA1 CRISPR single-cell cancer

Thompson(Larry H) Mutat Res 2012-11-06

...BRCA1, BRCA2, BLM, RAD51, and the MRE11-RAD50-NBS1 complex. Thus, the nature of the intricate coordination of repair pro...

Vanstone(Meredith),Chow(Winsion),Lester(Laur… Can Fam Physician 2012-12-20

...BRCA1 or BRCA2 gene mutations and the proportion of women who would have qualified, based on family cancer history, for ...

Panier(Stephanie),Ichijima(Yosuke),Fradet-Tu… Mol Cell 2012-10-26

...BRCA1-interacting RAP80 protein accumulate at DSB sites through the use of bipartite modules composed of UBDs juxtaposed...

Kirchhoff(Tomas),Gaudet(Mia M),Antoniou(Anto… PLoS One 2012-11-27

...BRCA1 and 2,020 BRCA2 carriers from 11 centers in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Based...

Zander(Serge A L),Kersbergen(Ariena),Sol(Wen… Cancer Prev Res (Phila) 2012-12-20

...BRCA1-mutated breast cancer and examined tumor latency in K14cre;Brca1(F/F); p53(F/F), Abcb1a/b(-/-);K14cre;Brca1(F/F); ...

Lai(Dulcie),Visser-Grieve(Stacy),Yang(Xiaolo… Biosci Rep 2012-10-30

...BRCA1 (breast-cancer susceptibility gene 1), PTEN (phosphatase and tensin homologue deleted on chromosome 10), Hippo pat...

Heijnsdijk(Eveline A M),Warner(Ellen),Gilber… Cancer Epidemiol Biomarkers P… 2012-12-27

...BRCA1, P < 0.001]. Below the age of 40, one (invasive) cancer of the 25 screen-detected cancers in BRCA1 mutation carrie...

Arnedos(Monica),Bihan(Celine),Delaloge(Suzet… Ther Adv Med Oncol 2012-08-23

...BRCA1 mutation carriers has offered potential therapeutic avenues for patients with these cancers including poly (ADP-ri...

Ratner(Elena S),Sartorelli(Alan C),Lin(Z Pin… Curr Opin Oncol 2012-10-19

...BRCA1/2-deficient tumors.Given that hereditary EOC with deleterious BRCA1/2 mutations and BRCAness sporadic EOC are prof...

Yanowsky(Kira),Barroso(Alicia),Osorio(Ana),U… Breast Cancer Res Treat 2012-12-13

...BRCA1 and BRCA2. Since there is a link between DNA repair and telomere maintenance mechanisms, we have investigated for ...

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