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Molecular profile of residual triple-negative breast cancer: opportunities fo...

van den Ende(NS),Smid(M),Martens(JWM),Debe... NPJ Breast Cancer 2026-05-13

...BRCA1/2, PIK3CA, and RB1, have been associated with favorable responses to targeted therapeutics in clinical trials. Mor...

AZD6738 overcomes acquired olaparib resistance in BRCA1 mutation triple-negat...

Huang(L),Yang(Y),Dai(L),Zhou(J),Shao(J),Qi... Sci Rep 2026-05-12

...BRCA1/2 mutations, resistance inevitably emerges in TNBC patients. Ataxia telangiectasia and Rad3-related (ATR) protein ...

Real-world data on oncology in Morocco: a narrative review of four decades of...

Lkhoyaali(S),Ghizlane(C),Batlamous(B),Efou... J Cancer Res Clin Oncol 2026-05-13

...BRCA1/2, and VEGF.56 CONCLUSION: Morocco has transitioned from case-series oncology research to integrated molecular-epi...

Liquid Biopsy in Advanced Prostate Cancer.

Mediavilla-Medel(P),García-Simón(N),Gonzál... Cancers (Basel) 2026-04-24

...BRCA1/2 and ATM mutations, guiding targeted therapies, and enabling real-time monitoring of treatment response and resis...

Genomic Predictors of Platinum Resistance and Survival in High-Grade Serous O...

De Marco(C),Rocca(V),Migliozzi(S),Venezian... Cancers (Basel) 2026-04-28

...BRCA1/2) exhibited significantly worse survival compared with both BRCA1/2-mutated cases and the overall cohort. Conclus...

NBR1-Mediated Selective Autophagy in Plant Development and Stress Responses.

Li(X),Duan(Y),Zhou(J),Yu(P) Plants (Basel) 2026-04-28

...BRCA1 GENE1 (NBR1) is one of the best-characterized. NBR1 mediates the selective turnover of ubiquitinated or stress-dam...

Enhanced Detection of BRCA Copy Number Alterations Within a Commercial HRD As...

De Bonis(M),Iapicca(P),De Paolis(E),Brisig... Int J Mol Sci 2026-04-29

...BRCA1/2 (BRCA) genes in ovarian cancer (OC). We evaluated the performance of a high-resolution algorithm integrated into...

Brca1 heterozygosity leads to hepatic steatosis in male and female mice despi...

Palikhe(S),Qiao(L),Kutz(C),Liang(X),Dhoraj... bioRxiv 2026-02-26

...Brca1 +/- mice. These findings identify Brca1 heterozygosity as a modifier of metabolic disease risk, expanding BRCA1 bi...

Advances in PARP Inhibition in Improving Outcomes of Breast Cancer, Ovarian C...

Latif(M),Mazhar(S),Tasleem(M),Alqurashi(A)... Drug Des Devel Ther None

...BRCA1/2 in BC and OC, highlighting key discovery milestones and providing an overview of available PARP inhibitors (PARP...

Case Report: Niraparib-abiraterone in HRR-mutated metastatic castration-resis...

Vascotto(IA),Catalano(M),Venturini(J),Cala... Front Oncol None

...BRCA1/2 (three BRCA2, two BRCA1), and one patient with concurrent PALB2. Median age at therapy initiation was 70 years (...

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