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A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved i…

Walker(JA),Bernards(A) Rare Dis 2014-00-00

...NF1) is caused by loss of a negative regulator of Ras oncoproteins. Unknown genetic modifiers have been implicated in NF...

Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial dif…

Lee(DY),Yeh(TH),Emnett(RJ),White(CR),Gutmann… Genes Dev 2010-10-15

...Nf1 loss leads to increased NSC proliferation and gliogenesis in the brainstem, but not in the cortex. Using Nf1 genetic...

Preclinical evaluation of the combination of mTOR and proteasome inhibitors wit…

Yamashita(AS),Baia(GS),Ho(JS),Velarde(E),Won… J Neurooncol 2014-05-00

...NF1) mutations. NF1 is a tumor suppressor gene essential for negative regulation of RAS signaling. Survival for MPNST pa...

The role of nerve microenvironment for neurofibroma development.

Liao(Chung-Ping),Pradhan(Sanjay),Chen(Zhiguo… Oncotarget 0000-00-00

Deregulation of RAS signaling in Neurofibromatosis type 1 (NF1) results in the development of multiple neurofibromas, co...

Impaired synaptic plasticity in RASopathies: a mini-review.

Mainberger(Florian),Langer(Susanne),Mall(Vol… J Neural Transm (Vienna) 0000-00-00

...NF1)], neurocognitive impairments are frequent and are affected by components of the RAS pathway which lead to impairmen...

Neurofibromatosis 1-associated panhypopituitarism presenting as hypoglycaemic s…

Waheed(Waqar),Nathan(Muriel H),Allen(Gilman … BMJ Case Rep 2016-09-13

A 37-year-old man with a known history of neurofibromatosis 1 (NF1) presented within 2 days of diarrhoeal illness follow...

Coexisting Optic Pathway and Posterior Fossa Gliomas in an Adult With Previousl…

Pinto(C),Santos(AP),Faia(J),Pinheiro(IS),Mar… Cureus 2026-03-00

Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder that predisposes to central nervous system (CNS) ...

Highly Active Relapsing-Remitting Multiple Sclerosis with Neurofibromatosis Typ…

Lemonaris(M),Kleopa(KA) Case Rep Neurol 2024-00-00

Multiple sclerosis (MS) is an autoimmune neurodegenerative disease which can rarely co-exist with neurofibromatosis 1 (N...

Malignant peripheral nerve sheath tumor of the cervix in an adolescent with neu…

Furuzono(N),Togami(S),Kitazono(I),Nishikawa(… J Obstet Gynaecol Res 2024-12-00

...NF1). This report describes a cervical MPNST in an 18-year-old patient with no history of sexual activity, abnormal vagi...

Correction of cervical kyphoscoliosis, bisected spinal cord, and vertebral arte…

LeFever(D),Hanks(T),Kumar(R),Louie(P),Levequ… J Craniovertebr Junction Spine 2024-00-00

Neurofibromatosis-1 (NF1) presents complex challenges due to its multisystemic effects, including kyphoscoliosis, dural ...

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