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Tripathi(U),Singh(R) Mol Biol Rep 2026-04-27

...BRCA1 expression is essential for high-fidelity HR, and its deficiency may promote error-prone NHEJ. Similarly, a low NA...

Jiang(W),Tang(TT),Ni(WJ),Wei(JX),Jiang(LY)... Adv Sci (Weinh) 2026-07-00

...BRCA1 and increase BRCA1 expression to safeguard TECs against DNA damage, thereby promoting cellular proliferation and s...

Melanson(A),Alsuhaibani(M),Viezel-Mathieu(... Fam Cancer 2026-04-28

BACKGROUND: Women with germline pathogenic variants (GPV) in BRCA1/2, PALB2, or other high penetrance genes may consider...

Deniz(C),Yüksel(B),Cebeci(E),Şahin(F) Mol Cell Biochem 2026-06-00

...BRCA1/2, RAD51, and CDK1/2/4/6), supporting a role for cell cycle arrest and DNA damage modulation in mediating these ef...

Akamandisa(MP),Xia(M),Cheah(W),Wubbenhorst... JCI Insight 2026-06-22

...BRCA1/2 pathogenic variants (gBRCA1/2 PVs) have elevated young-onset breast cancer risk. To define the pretreatment geno...

VanderVere-Carozza(PS),Jordan(MR),Garrett(... Nucleic Acids Res 2026-04-23

...BRCA1-deficient breast and ovarian cancer models, we demonstrate that RPA is critical for sustaining replication fork sp...

Nezafati(P),Vilain(R),Singh(T) Front Oncol None

...BRCA1-associated protein 1 (BAP1). There was no invasive growth and therefore, the appearance for concerning for mesothe...

Barron(CR),Ramineni(M),Finkelman(BS),Zhang... Hum Pathol 2026-08-00

...BRCA1 mutations (gBRCA1) were limited, mostly with small cohorts and had generally been conducted on unselected BC cases...

Tostrud(L),Turkmen(SB),Zhang(J),Hodan(R),K... J Med Genet 2026-07-23

...BRCA1, BRCA2, BRIP1, CHEK2, MSH6, PMS2 and ATM. Only a personal history of cancer other than USC was independently assoc...

Spellecy(O),Qadir(J),Han(R),Zhu(K),Xu(B),Z... Oncogene 2026-07-00

...BRCA1/2-deficient TNBC, integrin-FAK and NAMPT/NAD+ pathways converged on Wnt/β-catenin signaling to regulate DNA repair...