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TP53 BRCA1 CRISPR single-cell cancer

Padeganeh(Abbas),De Rop(Valérie),Maddox(Paul… Chromosome Res 2013-09-03

The Centromere is a unique chromosomal locus where the kinetochore is formed to mediate faithful chromosome partitioning...

Tachiwana(Hiroaki),Miya(Yuta),Shono(Nobuaki)… Nucleic Acids Res 2013-05-02

CENP-B is a widely conserved centromeric satellite DNA-binding protein, which specifically binds to a 17-bp DNA sequence...

Gonzalez(Marlyn),He(Haijin),Sun(Siyu),Li(Che… Proc Natl Acad Sci U S A 2013-03-07

Centromeric histone CENP-A, a variant of canonical histone H3, plays a central role in proper chromosome segregation. Lo...

Dellavance(Alessandra),Alvarenga(Rossana Ras… J Immunol Methods 2013-05-17

To report on a novel immunofluorescence pattern specifically associated with antibodies to SS-A/Ro.,A novel immunofluore...

Malvezzi(Francesca),Litos(Gabriele),Schleiff… EMBO J 2013-04-02

The Ndc80 complex is the key microtubule-binding element of the kinetochore. In contrast to the well-characterized inter...

Nishino(Tatsuya),Rago(Florencia),Hori(Tetsuy… EMBO J 2013-04-02

The kinetochore forms a dynamic interface with microtubules from the mitotic spindle during mitosis. The Ndc80 complex a...

Dun(Boying),Sharma(Ashok),Xu(Heng),Liu(Haita… Am J Transl Res 2013-12-18

Inhibition of inosine monophosphate dehydrogenase (IMPDH) by mycophenolic acid (MPA) can inhibit proliferation and induc...

French(Bradley T),Straight(Aaron F) Nat Cell Biol 2013-11-13

Faithful genome segregation depends on the functions of the eukaryotic centromere, which is characterized by the histone...

Gardner(Melissa K) Nat Cell Biol 2013-11-13

During mitosis, kinetochores attach to microtubule plus ends, thus allowing dynamic microtubules to properly segregate c...

Carone(Dawn M),Zhang(Chu),Hall(Laura E),Ober… Chromosome Res 2013-09-03

The proper functioning of centromeres requires a complex cascade of epigenetic events involving chromatin and kinetochor...

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