...BRCA1 or BRCA2 pathogenic variants. While risk-reducing salpingo-oophorectomy remains the standard for prevention, confe...
...BRCA1/BRCA2 mutations. This retrospective, single-center study included women younger than 50 years with confirmed BRCA1...
...BRCA1, BRCA2, MRE11 and RAD51). Our study demonstrates that the combined intervention of rUCMSC-EVs and chemotherapy dru...
...BRCA1, BRCA2, PALB2, RAD51D, and MSH6 were associated with a 1.3 to twofold abundance of CD163-positive cells. Estrogen ...
...BRCA1/2 mutations (BRCAm) in the Netherlands. As randomized clinical trials include fitter patients, their findings may ...
...BRCA1/2 guidelines and/or multifactorial likelihood analysis. For variants with concordant SGE functional results, eithe...
...BRCA1/2 and Lynch syndrome variants declined with age; BRCA2 exceeded BRCA1 in patients ≥70. Moderate-penetrance variant...
...BRCA1), and was accompanied by increased DNA damage at late/post-EGA stages. Induced DNA damage upregulated transcripts ...
...BRCA1 and BRCA2 genes. The introduction of high throughput sequencing methods has enabled the identification of a broade...
...BRCA1 and BRCA2 mutations, mismatch repair status, as well as other established and emerging biomarkers. Emphasis is pla...
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