Literature Search

Yang(FC),Chen(S),Robling(AG),Yu(X),Nebesio(T… J Clin Invest 2006-11-00

...Nf1(+/-) mice contain elevated numbers of multinucleated osteoclasts. Both osteoclasts and osteoclast progenitors from N...

Moles(KJ),Gowans(GC),Gedela(S),Beversdorf(D)… Genet Med 2012-05-00

...NF1) is an autosomal dominant disorder caused by mutations of the neurofibromin 1 (NF1) gene at 17q11.2. Approximately 5...

Jang(MA),Kim(YE),Kim(SK),Lee(MK),Kim(JW),Ki(… J Hum Genet 2016-08-00

...NF1 patients who showed splicing alterations in reverse transcription-PCR of NF1 mRNA and identified 24 different NF1 sp...

Cohen-Barak(E),Toledano-Alhadef(H),Danial-Fa… Exp Dermatol 2022-00-00

...NF1) is caused by germline mutations in the NF1 gene and manifests as proliferation of various tissues, including plexif...

Giraud(JS),Bièche(I),Pasmant(É),Tlemsani(C) Expert Opin Investig Drugs 2023-00-00

...NF1 somatic alteration frequency is higher (~15%). However, to date, the therapeutic impact of NF1 somatic alterations i...

Darle(A),Mahiet(T),Aubin(D),Doyen(M),El Kass… Front Cell Dev Biol 2024-00-00

...NF1) is one of the most common genetic disorders caused by heterozygous germline NF1 mutations. NF1 affects many systems...

Allaway(RJ),Wood(MD),Downey(SL),Bouley(SJ),T… Oncotarget 2018-03-23

...NF1 or loss of the NF1 protein is also observed in glioblastoma, lung adenocarcinoma, and ovarian cancer among other spo...

Sheikh(TN),Patwardhan(PP),Cremers(S),Schwart… Oncotarget 2017-11-07

...NF1 knockdown in wild-type NF1 cell line shows increased sensitivity to glutaminase inhibition. Conversely, NF1 overexpr...

Walker(JA),Upadhyaya(M) Expert Opin Ther Targets 2018-00-00

...NF1 gene encodes neurofibromin, which functions as a negative regulator of RAS. NF1 is a chronic multisystem disorder af...

Castricum(J),Tulen(JHM),Taal(W),Ottenhoff(MJ… Clin Neurophysiol 2020-00-00

...NF1. Overall, the TMS response was significantly lower in NF1 patients (F(1, 41) = 7.552, p = 0.009). Individuals with N...