...NF1 in our patient could be attributed to mosaic hemizygosity for the NF1 gene in some of her somatic cells. A similar m...
...NF1. We show that NF1 loss activates a bypass pathway, which confers ERK dependency downstream of RAS activation. These ...
...NF1 and NF2 cases shows that the ratio of NF2:NF1 in childhood is approximately 1:100, and that the clinical features of...
Thoracic meningoceles (tMCs) are extremely rare, yet the majority occur in patients with Neurofibromatosis type 1 (NF1)....
...NF1-mutant breast cancer patient. This multi-organoid system enabled individualized assessment of drug absorption, distr...
...NF1). Both conditions typically involve café-au-lait macules, axillary freckling, and macrocephaly; however, patients wi...
Optic pathway gliomas are often asymptomatic tumors occurring in children with neurofibromatosis type 1 (NF1 + OPG) or s...
...NF1) loss of function (LoF) mutations are frequent in melanoma and drive hyperactivated RAS and tumor growth. NF1LoF mel...
...NF1. For neurofibromatosis type 1 and 2, we compared the mechanism of germline deletion. Unlike NF1, where three specifi...
...NF1 and prioritized attention as the first domain of focus given prior and current trends in NF1 cognitive clinical tria...
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