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Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppre…

Ramkissoon(A),Chaney(KE),Milewski(D),William… Clin Cancer Res 2019-00-01

In neurofibromatosis type 1 (NF1) and in highly aggressive malignant peripheral nerve sheath tumors (MPNSTs), constituti...

A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, ra…

Ullrich(NJ),Prabhu(SP),Reddy(AT),Fisher(MJ),… Neuro Oncol 2020-00-14

...NF1-associated pediatric LGGs. Children with radiologic-progressive, NF1-associated LGG and prior treatment with a carbo...

Modulation of spine fusion with BMP-2, MEK inhibitor (PD0325901), and zoledroni…

Bobyn(JD),Deo(N),Little(DG),Schindeler(A) J Orthop Sci 2021-07-00

...NF1). Moreover, deficiencies in NF1-Ras-MEK signaling affect bone formation and resorption that in turn impacts on spine...

NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK…

Weiss(BD),Wolters(PL),Plotkin(SR),Widemann(B… J Clin Oncol 2021-00-01

...NF1 and PNs and is the first published response study for MAPK/ERK kinase inhibitors in adults with NF1 and PNs. Mirdame...

Brain morphometric analysis in neurofibromatosis 1.

DiMario(FJ),Ramsby(GR),Burleson(JA) Arch Neurol 1999-11-00

To investigate the relationships between brain and skull base growth in patients with neurofibromatosis 1 (NF1) compared...

Treatment options for optic pathway gliomas.

Thomas(Reena P),Gibbs(Iris C),Xu(Linda Wei),… Curr Treat Options Neurol 2015-01-26

...NF1 can also be observed initially because of their favorable prognosis. Children with NF1 and chiasmal or posterior vis...

Distal fusion vertebra selection in neurofibromatosis type 1 scoliosis: integra…

Zhang(Y),Shao(XX),Chen(J),Deng(YL),Zhang(TY)… Eur Spine J 2026-05-21

...NF1) scoliosis is traditionally guided by adolescent idiopathic scoliosis (AIS) criteria, which do not account for NF1-s...

Selumetinib in Japanese pediatric patients with neurofibromatosis type 1 and sy…

Suenobu(S),Terashima(K),Akiyama(M),Oguri(T),… Neurooncol Adv 2023-00-00

Plexiform neurofibromas (PN) are a manifestation of neurofibromatosis type 1 (NF1) that may cause morbidity and impact h...

Age-varying associations between parent-reported executive function and interna…

Liu(D),Zong(X),Wolters(PL),Walsh(KS),Janusz(… J Int Neuropsychol Soc 2026-05-00

...NF1), a genetic condition underrepresented in psychiatric research. Cross-sectional data of 1,049 observations from 803 ...

Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit criti…

Pan(Y),Smithson(LJ),Ma(Y),Hambardzumyan(D),G… Oncotarget 2017-05-16

...NF1 loss. We further show that the NF1 protein, neurofibromin, negatively regulates Ccl5 expression through suppression ...

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