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Brca1 heterozygosity leads to hepatic steatosis in male and female mice despi...

Palikhe(S),Qiao(L),Kutz(C),Liang(X),Dhoraj... bioRxiv 2026-02-26

...Brca1 +/- mice. These findings identify Brca1 heterozygosity as a modifier of metabolic disease risk, expanding BRCA1 bi...

Advances in PARP Inhibition in Improving Outcomes of Breast Cancer, Ovarian C...

Latif(M),Mazhar(S),Tasleem(M),Alqurashi(A)... Drug Des Devel Ther None

...BRCA1/2 in BC and OC, highlighting key discovery milestones and providing an overview of available PARP inhibitors (PARP...

Case Report: Niraparib-abiraterone in HRR-mutated metastatic castration-resis...

Vascotto(IA),Catalano(M),Venturini(J),Cala... Front Oncol None

...BRCA1/2 (three BRCA2, two BRCA1), and one patient with concurrent PALB2. Median age at therapy initiation was 70 years (...

Factors influencing uptake of risk-reducing mastectomy among unaffected Israe...

Laitman(Y),Aharon(K),Schloss(T),Margolin(L... Fam Cancer 2026-05-13

Women harboring pathogenic variant (PV) in the BRCA1 or BRCA2 genes (= BRCA) have an elevated lifetime risk for breast c...

Prevalence and clinical significance of germline pathogenic variants identifi...

Kano(M),Taruno(K),Inuzuka(M),Makino(R),Tak... Breast Cancer 2026-07-00

...BRCA1/2 and non-BRCA genes. Thus, MGPT may be an effective approach to support appropriate clinical management for both ...

Hereditary cancer syndromes with gynecological cancer risk: focus on preventi...

Duranti(S),Iacobelli(V),Trozzi(R),Camarda(... Front Oncol None

...BRCA1/2 and mismatch-repair genes, confer a substantial risk of several malignancies, including ovarian, endometrial, an...

Retrospective cohort study on cervicovaginal swabs for the non-invasive molec...

Han(D),Zhang(S),Jin(Y),Chen(X),Yan(H),Peng(Y) Front Oncol None

...BRCA1, and BRCA2; DNA methylation profiling was analyzed using quantitative methylation-specific PCR (qMSP). Logistic re...

Decoding BRCA1 and BRCA2 Mutations in High-Grade Serous Ovarian Cancer: Impac...

Momi(M),Salviato(E),Ravaggi(A),Mazza(C),To... Int J Gynecol Cancer 2026-06-00

...BRCA1/2 mutations, and 100 wild-type controls. Mutations were categorized based on gene (BRCA1 vs BRCA2), location (insi...

Co-Pathogenic Role of BRCA1 and OBSCN Deletions in Chinese Familial Breast Ca...

Yi(L),Chen(K),Wang(D),Wang(R),Zhu(X),Chai(... Am J Case Rep 2026-05-02

...BRCA1 and OBSCN was the main cause of breast cancer in this family. The simultaneous association of 2 genes with the occ...

Synergistic antitumor effect between Olaparib and Chidamide by regulation of ...

Zhu(L),Ji(Z),Wang(X),Xin(J),Ma(L),Zhang(R)... Anticancer Drugs 2026-08-01

...BRCA1, a main member of DNA damage repair. Simultaneously, Olaparib-induced inhibition of PARP expression leads to the '...

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