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Maletta(M),Vicenti(R),Forastiere(C),Di San... J Ovarian Res 2026-02-07

Germline mutations of BRCA1 and BRCA2 may impair DNA repair in the ovarian cortex, leading to increased oocyte apoptosis...

Can(ND),Akcay(IM),Celik(E),Ciftci(C),Unal(... Hum Genomics 2026-02-08

...BRCA1, BRCA2, PALB2, CHEK2, and ATM, while in CRC patients PVs were enriched in MLH1, MUTYH, MSH2, and CHEK2. Notably, C...

Cui(H),Zhu(M),Ling(B),Zhang(L) Am J Cancer Res None

...BRCA1/2 mutation frequency was 15.61%, and two previously unreported variants, BRCA1 NM_007294.3:c.4185G>A and BRCA2 NM_...

Smith(CE),Sandfeld(EK),Cherian(S),Rose(PG) Gynecol Oncol Rep 2026-02-00

...BRCA1 mutation and recurrent high-grade serous carcinoma following secondary cytoreduction with right hepatectomy and di...

Lang(GT),Weng(XL),Liu(Y),Hu(X),Shao(ZM),Hu(Z) Pathophysiology 2026-01-20

...BRCA1, BRCA2, and PALB2 variants, we delineated the genomic landscape of 96 MaBC cases. Subsequent whole-exome sequencin...

Liguori(L),Polcaro(G),Pagliara(V),De Feo(R... Curr Oncol Rep 2026-02-20

...BRCA1 protein, modulating its function. While inactivating somatic and germline mutations in BRCA1 are well-known to be ...

Suizu(E),Koyanagi(T),Saga(Y),Takahashi(Y),... Cureus 2026-01-00

...BRCA1/2 wild-type ovarian cancer cell line SHIN-3 (PR-negative and mPR-positive), which is considered resistant to PARP ...

Ishida(H),Takashima(A) Cureus 2026-01-00

...BRCA1 and BRCA2 variants. RRSO has been shown to markedly reduce the risk of ovarian cancer and to confer a protective e...

Uzaif(Q) In Silico Pharmacol None

...BRCA1 (BRCT domain), and docked favorably with DNA (PDB ID: 1TUP), demonstrating that DNA-binding capability remained in...

Widschwendter(M),Herzog(C),Rasul(MF),Bogga... Commun Med (Lond) 2026-02-11

...BRCA1/2 pathogenic variant carriers. However, their impact on endometrial safety remains insufficiently characterized, r...