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Distinct functions of mammalian RAD51 paralogs in genome maintenance.

Dwivedi(HK),Bhattacharya(D),Kadupatil(S),Nag… Biochem Soc Trans 2026-09-23

...RAD51C, RAD51D, XRCC2, and XRCC3) are evolutionarily conserved essential proteins for cell survival and genome maintenan...

Biphasic (squamoid) papillary renal cell carcinoma: a distinct molecular and mo…

Lu(Z),Zhou(Y),Fan(W),Choksi(S),Sultan(L),Kat… Virchows Arch 2026-09-00

...RAD51C/D), and chromatin remodeling genes (EZH2, ARID1A). These findings support BPRCC as a distinct subtype of papillar...

Therapeutic effects of G90'-ES2 protein complex from regenerated Eisenia fetida…

Yang(Y),Ni(P),Ma(L),Tang(H),Yang(J),Zhou(X),… J Ethnopharmacol 2026-01-30

...RAD51C, TCTP, and SCBP2) in G90'-ES2 might hold particular importance for its therapeutic effect against RISI. This inve...

Monoallelic germline RAD51C, RAD51D, and BRIP1 variants in hereditary cancer te…

Özdemir-Pehlivan(Z),Büke(A),Çevik-Demir(E),S… Mutat Res 2026-06-19

...RAD51C, RAD51D, and BRIP1 identified through hereditary cancer multigene panel testing in a real-world cohort of approxi...

Frequency of germline pathogenic variants in breast cancer predisposing genes i…

Metcalfe(K),Narod(SA),Poll(A),Hoey(C),Warner… Br J Cancer 2026-06-23

...RAD51C, EPCAM, MLH1, MSH2, MSH6, and PMS2). Prevalence of pathogenic variants (PVs) was estimated by age, family history...

Genomic Profiling of Breast Cancer in an Ecuadorian Cohort Reveals Clinically R…

Zambrano(AK),Tamayo-Trujillo(R),Guevara-Ramí… Cancers (Basel) 2026-06-17

...RAD51C, MSH6, NF1, CYLD, and SDHB. Variants of uncertain significance represented 66.7% of all detected variants and aff...

The Impact of Pathogenic Variants of BRCA1, BRCA2, and other DNA-Repair Genes o…

Zeng(X),Levin(G),Shahbazian(L),Ribeiro(R),We… J Obstet Gynaecol Can 2026-07-03

...RAD51C/D, 1 (2%) PALB2, and 1 (2%) CHEK2. The median follow-up time was 27 months. Groups were balanced with respect to ...

Moonlighting role of meiotic SYCP1 in breast cancer: A chromatin-bound regulato…

Brennan(LC),Grinchuk(OV),Pachon-Penalba(M),S… Sci Adv 2026-07-10

...RAD51C, and H2AX. Loss of SYCP1 impairs DNA repair kinetics, attenuates tumor cell proliferation and migration, and incr...

Olaparib in HR-deficient, metastatic triple-negative breast and platinum-sensit…

Sjoquist(KM),Dobrovic(A),Robledo(KP),Nesic(K… Br J Cancer 2026-07-08

...RAD51C (meRAD51C) or mutation of non-BRCA HR genes. This trial evaluated olaparib in platinum-sensitive, relapsed HGSOC ...

Routine germline genetic testing in 3552 unselected NHS breast cancer patients:…

Torr(B),Mansour(L),Fierheller(CT),Hamill(M),… NPJ Breast Cancer 2026-07-09

...RAD51C/RAD51D). Designing 'Ultra-simple' eligibility criteria suitable for mainstreaming, detection (sensitivity) could ...

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