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Isolated and combined dystonia syndromes - an update on new genes and their phe…

Balint(B),Bhatia(K P) Eur J Neurol 2015-09-28

...TAF1 mutations, which rarely can also manifest in women. Clinical and genetic heterogeneity also characterizes myoclonus...

Effects of lactoferrin on intestinal epithelial cell growth and differentiation…

Blais(Anne),Fan(Cuibai),Voisin(Thierry),Aatt… Biometals 2015-07-24

...TAF1 expression; these proteins being implicated in the regulation of numerous genes related to cellular proliferation a...

Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal …

Severson(Paul L),Vrba(Lukas),Stampfer(Martha… Mutat Res Genet Toxicol Envir… 2015-01-21

...TAF1 in 184Aa; PIK3CG, HSP90AB1, WHSC1L1, LCP1 in 184Be and FANCA, LPP in 184Ce. Biological processes that typically har...

Biased multicomponent reactions to develop novel bromodomain inhibitors.

McKeown(Michael R),Shaw(Daniel L),Fu(Harry),… J Med Chem 2015-03-03

...TAF1, a bromodomain-containing transcription factor previously unapproached by discovery chemistry. Compound 32 was cocr...

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reve…

Wang(Hui),Curran(Elizabeth C),Hinds(Thomas R… Cell Res 2015-07-10

...TAF1. The TAF1-TAF7 complex displays an inter-digitated compact architecture, featuring an unexpected TAF1 winged helix ...

Dystonia, facial dysmorphism, intellectual disability and breast cancer associa…

Moscovich(Mariana),LeDoux(Mark S),Xiao(Jianf… BMC Med Genet 2014-09-10

...TAF1). Secondary dystonia is also a relatively common clinical sign in many neurogenetic disorders. However, the contrib...

Dystonia.

Morgante(Francesca),Klein(Christine) Continuum (Minneap Minn) 2014-05-15

...TAF1 most likely but not yet proven to be linked to DYT3) and paroxysmal (PNKD [DYT8], PRRT2 [DYT10], and SLC2A1 [DYT18]...

Transcriptional coactivator CIITA, a functional homolog of TAF1, has kinase act…

Soe(Katherine C),Devaiah(Ballachanda N),Sing… Biochim Biophys Acta 2014-01-02

...TAF1, a component of the general transcription factor complex TFIID. TAF1 and CIITA both possess intrinsic acetyltransfe...

Genetics of dystonia: what's known? What's new? What's next?

Lohmann(Katja),Klein(Christine) Mov Disord 2014-02-26

...TAF1 [DYT3], GCHI [DYT5], SGCE [DYT11], ATP1A3 [DYT12]), PRKRA (DYT16), and paroxysmal (MR-1 [DYT8], PRRT2 [DYT10], SLC2...

Structural and functional insight into TAF1-TAF7, a subcomplex of transcription…

Bhattacharya(Suparna),Lou(Xiaohua),Hwang(Pet… Proc Natl Acad Sci U S A 2014-08-18

...TAF1 and known histone acetyltransferases. Instead, the surface of the TAF1-TAF7 complex contains two prominent conserve...

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