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Transactivation of the WT1 antisense promoter is unique to the WT1[+/-] isoform.

Moorwood(K),Salpekar(A),Ivins(SM),Hall(J),Po… FEBS Lett 1999-07-30

...WT1 promoter that contains WT1 consensus sites, but is transcriptionally activated by WT1. In this study, we demonstrate...

Recognition of a natural WT1 epitope by a modified WT1 peptide-specific T-cell …

Tamanaka(T),Oka(Y),Fujiki(F),Tsuboi(A),Katsu… Anticancer Res 2012-12-00

...WT1(235) peptide but also with the natural WT1(235) peptide and lysed modified or natural WT1(235) peptide-pulsed target...

Identification of a Novel C-Terminal Truncated WT1 Isoform with Antagonistic Ef…

Tatsumi(N),Hojo(N),Sakamoto(H),Inaba(R),Mori… PLoS One 2015-00-00

...WT1 isoform exerted dominant negative effects on anti-apoptotic function of major WT1 isoforms. Ex4a(+)WT1 isoform was e...

Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer W…

Tsuboi(A),Oka(Y),Udaka(K),Murakami(M),Masuda… Cancer Immunol Immunother 2002-12-00

...WT1 peptide (CYTWNQMNL) elicited WT1-specific cytotoxic T lymphocytes (CTL) more effectively than the natural 9-mer WT1 ...

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia.

Gaiger(A),Reese(V),Disis(ML),Cheever(MA) Blood 2000-08-15

...WT1-specific antibody, demonstrating that WT1 can be immunogenic in the context of cancer cells. To evaluate whether WT1...

WT1 Trio Peptide-Based Cancer Vaccine for Rare Cancers Expressing Shared Target…

Oji(Y),Kagawa(N),Arita(H),Naka(N),Hamada(KI)… Cancers (Basel) 2023-01-06

...WT1 Trio was 62.9%, which was not significantly different from 60.7% in the WT1-235 CTL peptide vaccine. The WT1 Trio sa...

Mosaic and polymorphic imprinting of the WT1 gene in humans.

Jinno(Y),Yun(K),Nishiwaki(K),Kubota(T),Ogawa… Nat Genet 1994-03-00

...WT1) in human tissues. We confirm that WT1 is biallelically expressed in the kidney, however, in five of nine preterm pl...

RNA editing in the Wilms' tumor susceptibility gene, WT1.

Sharma(PM),Bowman(M),Madden(SL),Rauscher(FJ)… Genes Dev 1994-03-15

...WT1 cDNAs contain either a thymidine or a cytosine residue at position 839. Genomic WT1 DNA contains only T839. To expla...

Identification of an antisense WT1 promoter in intron 1: implications for WT1 g…

Malik(KT),Wallace(JI),Ivins(SM),Brown(KW) Oncogene 1995-10-19

...WT1 gene, we have identified an antisense WT1 promoter operational in the opposite direction relative to the 5' promoter...

Targeting of the WT191-138 fragment to human dendritic cells improves leukemia-…

Dagvadorj(N),Deuretzbacher(A),Weisenberger(D… Cancer Immunol Immunother 2017-03-00

...WT1 as DC-targeting recombinant WT1 vaccines (anti-hDEC205-WT1). Of all anti-hDEC205-WT1 fusion proteins designed for ov...

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