...BRCA1 or BRCA2 (BRCA1/BRCA2) mutations of any cancer type and is a highly chromosomally unstable disease. Despite the in...
...BRCA1, BRCA2, CHEK2, and ATM. While radiotherapy (RT) is a crucial component of breast cancer (BC) treatment, its potent...
...BRCA1 and BRCA2) remain central to hereditary breast and ovarian cancers, progress in cancer genetics has shifted clinic...
...BRCA1 (6.46%). Missense (35.5%) and frameshift (32.3%) variants predominated. A high number of PVs was found in individu...
...BRCA1, and BRCA2), telomere length maintenance (TERT), DNA damage response (FGFR2), and DNA repair (CHD1) are recognized...
...BRCA1 and BRCA2 function are linked to hereditary breast and ovarian cancers. As BRCA1 and BRCA2 are critical for homolo...
...BRCA1, BRCA2, MLH1, and MSH2 mutations. This was a multi-site, retrospective cohort study including women aged 21-45 yea...
...BRCA1-/BRCA2-containing complex 3 (BRCC3) in PD-related mechanisms such as ubiquitin-proteasome system dysfunction. This...
...BRCA1 locus was also identified; however, its biological significance remains uncertain. This case provides exome-wide s...
...BRCA1/2 direct targeted therapies. The article highlights the diagnostic value of entity-specific fusions and mutations,...
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