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Rethinking ovarian cancer III: the past decade and future directions.

Balkwill(FR),Laumont(CM),Burdett(N),Le Sau... Nat Rev Cancer 2026-06-00

...BRCA1 or BRCA2 (BRCA1/BRCA2) mutations of any cancer type and is a highly chromosomally unstable disease. Despite the in...

Risk of Radiation-Associated Contralateral Breast Cancer in Germline Mutation...

Prihharsanti(CHN),Prajoko(YW),Respati(DRP)... Cancers (Basel) 2026-03-29

...BRCA1, BRCA2, CHEK2, and ATM. While radiotherapy (RT) is a crucial component of breast cancer (BC) treatment, its potent...

Genetic Testing in Breast Cancer: Narrative Review and Clinical Insights.

Bistriceanu(I),Ungureanu(CO),Stoica(RA),Gi... Maedica (Bucur) 2026-03-00

...BRCA1 and BRCA2) remain central to hereditary breast and ovarian cancers, progress in cancer genetics has shifted clinic...

Germline pathogenic variant spectrum and prevalence among colorectal cancer p...

Baltayev(N),Abdikerim(S),Afonin(G),Rasulov... Sci Rep 2026-04-14

...BRCA1 (6.46%). Missense (35.5%) and frameshift (32.3%) variants predominated. A high number of PVs was found in individu...

MMTV Virus Detection, Survival Analysis, and Prognostic Relevance of Six Tumo...

Alamri(S),Awadalla(M),Henawi(RA),Al-Hazzaa... Int J Breast Cancer None

...BRCA1, and BRCA2), telomere length maintenance (TERT), DNA damage response (FGFR2), and DNA repair (CHD1) are recognized...

Functional assays for BRCA1 and BRCA2 variant analysis: new tools and their a...

Bose(M),Faseela(EE),Rossing(M),Sørensen(CS... NPJ Breast Cancer 2026-04-15

...BRCA1 and BRCA2 function are linked to hereditary breast and ovarian cancers. As BRCA1 and BRCA2 are critical for homolo...

Fertility desires and outcomes in patients with selected hereditary cancer sy...

Connelly(EA),Lowry(CM),Camara(C),Wei(J),Ga... Gynecol Oncol Rep 2026-06-00

...BRCA1, BRCA2, MLH1, and MSH2 mutations. This was a multi-site, retrospective cohort study including women aged 21-45 yea...

Post-transcriptional knockdown of BRCC3 via siRNA-loaded niosomes modulates a...

Gürel(Ç),Tut(E),Kuşçu(GC),Buhur(A),Germiya... J Drug Target 2026-05-07

...BRCA1-/BRCA2-containing complex 3 (BRCC3) in PD-related mechanisms such as ubiquitin-proteasome system dysfunction. This...

Illustrating the "Quiet Genome" Concept of SMARCA4 -Deficient Uterine Sarcoma...

Yoshida(H),Shiraishi(K),Yamanaka(T),Ishika... Int J Gynecol Pathol 2026-05-06

...BRCA1 locus was also identified; however, its biological significance remains uncertain. This case provides exome-wide s...

Twisted Tapestry of Tumors: Updates in Molecular Pathology of Breast Tumors.

Hoda(RS),Wen(HY) Surg Pathol Clin 2026-06-00

...BRCA1/2 direct targeted therapies. The article highlights the diagnostic value of entity-specific fusions and mutations,...

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