Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome characterized by an increased risk of malignant peripheral...
Selumetinib is the first approved treatment for pediatric patients with neurofibromatosis type 1 (NF1) and symptomatic, ...
...NF1-mutant tumors by triggering catastrophic oxidative stress. Specifically, we show that mTOR and HDAC inhibitors kill ...
The approval of selumetinib in patients with neurofibromatosis type 1(NF1) and inoperable plexiform neurofibromas (PN) h...
...NF1), 8 years after initial resection of primary bilateral adrenal pheochromocytomas without metastases. A 44-year-old w...
Selumetinib is approved for the treatment of pediatric patients with neurofibromatosis type 1 (NF1) who have symptomatic...
...NF1, and TP53(x2) genes and 30 variants of unknown significance (VOUS) in ABL1, ASXL1, ATM, BCOR, BCORL1, BRNIP3, CDH2, ...
A high proportion of patients with neurofibromatosis type 1 (NF1) present with functional hearing deficiency as a result...
...NF1-S) lacking pedicles in the apical area. We reviewed the NF1-S cases lacking pedicles diagnosed in our hospital betwe...
Non-optic gliomas occur in 5% of children with NF1, but little is known about these tumours in adults. We aimed to inves...
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