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TP53 BRCA1 CRISPR single-cell cancer

Cimadamore(A),Lopez-Beltran(A),Montironi(R... Surg Pathol Clin 2026-06-00

...BRCA1/2 testing in prostate cancer-has become critical for guiding treatment decisions.

Momeni-Boroujeni(A),Murali(R) Surg Pathol Clin 2026-06-00

...BRCA1/2, Lynch syndrome, Peutz-Jeghers syndrome, and DICER1.

Hanna(K),Levin(G),Al Nasir(M),Lacouline-Bo... Int J Gynecol Cancer 2026-04-09

...BRCA1mut, 19 (23.5%) were BRCA2mut, 15 (18.5%) tumors had no BRCA1 or BRCA2 mutations but exhibited a genomic instabilit...

Kang(MS),Katuwal(NB),Ghosh(M),Hong(SD),Jeo... Br J Cancer 2026-08-00

Poly(ADP-ribose) polymerase (PARP) inhibitors are highly effective therapies for BRCA1/2-mutated tumors. However, most p...

Fu(J),Wei(M),Xu(R),Zheng(X) Acta Biochim Biophys Sin (S... 2026-01-25

Receptor-associated protein 80 (RAP80) is a key component of the BRCA1-A complex and plays an essential role in recruiti...

Imaoka(T),Nagata(K),Nakamura(Y),Nishimura-... Ann ICRP 2026-05-07

...Brca1 variant. These findings demonstrate diverse interactions between radiation and different modifiers, emphasising ke...

Stopfer(JE),Horiguchi(M),Chittenden(A),Tso... JCO Oncol Pract 2026-05-07

...BRCA1, and CHEK2 being the most frequently identified. Disparities in testing completion were observed, with older age (...

Liu(YL),Gali(V),K Frey(M) Obstet Gynecol 2026-05-07

...BRCA1 / 2, but several other genes also contribute to risk of ovarian and breast cancers. Identification of pathogenic v...

Bu(R),Siraj(AK),Abdul Razzaq(EA),Iqbal(K),... Sci Rep 2026-05-07

...BRCA1/2-negative patients of Arab ancestry. We performed germline whole exome sequencing (WES) on a cohort of 79 BRCA1/2...

Fassari(A),Le Floc'h(B),Prudhomme(H),Ellou... Ann Surg Oncol 2026-05-08

...BRCA1-mutated breast cancer and complete situs inversus who presented with general deterioration and symptoms of high in...

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