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Kang(MS),Katuwal(NB),Ghosh(M),Hong(SD),Jeo... Br J Cancer 2026-08-00

Poly(ADP-ribose) polymerase (PARP) inhibitors are highly effective therapies for BRCA1/2-mutated tumors. However, most p...

Fu(J),Wei(M),Xu(R),Zheng(X) Acta Biochim Biophys Sin (S... 2026-01-25

Receptor-associated protein 80 (RAP80) is a key component of the BRCA1-A complex and plays an essential role in recruiti...

Imaoka(T),Nagata(K),Nakamura(Y),Nishimura-... Ann ICRP 2026-05-07

...Brca1 variant. These findings demonstrate diverse interactions between radiation and different modifiers, emphasising ke...

Stopfer(JE),Horiguchi(M),Chittenden(A),Tso... JCO Oncol Pract 2026-05-07

...BRCA1, and CHEK2 being the most frequently identified. Disparities in testing completion were observed, with older age (...

Liu(YL),Gali(V),K Frey(M) Obstet Gynecol 2026-05-07

...BRCA1 / 2, but several other genes also contribute to risk of ovarian and breast cancers. Identification of pathogenic v...

Bu(R),Siraj(AK),Abdul Razzaq(EA),Iqbal(K),... Sci Rep 2026-05-07

...BRCA1/2-negative patients of Arab ancestry. We performed germline whole exome sequencing (WES) on a cohort of 79 BRCA1/2...

Fassari(A),Le Floc'h(B),Prudhomme(H),Ellou... Ann Surg Oncol 2026-05-08

...BRCA1-mutated breast cancer and complete situs inversus who presented with general deterioration and symptoms of high in...

Yang(J),Song(L),Yin(R),Zhong(L) Front Oncol None

Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are well-established risk factors for breast, ovarian,...

González-Peramato(P),García-Fernández(E),J... Rev Esp Patol None

...BRCA1/2 and other HRR gene alterations in metastatic prostate cancer to support implementation in clinical practice.

Banerjee(M),Zaytseva(YY),Reusch(EM),Napier... Cancer Res 2026-05-15

...BRCA1 and ATM recruitment to γH2AX foci in an acetylation-dependent manner. Moreover, FASN inhibition-mediated DNA repai...