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Yu(Z),Peng(W),Li(M),Li(F),Zhang(T),Nong(Y)... Int J Surg 2026-02-05

...BRCA1, and RAD51 - significantly enriched in the HR pathway. Molecular docking and dynamic simulations indicate that RSV...

Nusawardhana(A),Nicolae(CM),Moldovan(GL) Nat Commun 2026-02-25

...BRCA1 and BRCA2 genes are observed in breast, ovarian, and other cancers. This results in defective homologous recombina...

Manirakiza(AVC),Freeman(JQ),Zhao(F),Keel(E... Res Sq 2026-05-05

...BRCA1: 39% and BRCA2: 18%) and 17.5% had moderate penetrance PVs; Rate of disclosure of PV to at least one family member...

Alobaidi(A),Rai(V) Explor Target Antitumor The... None

...BRCA1 mutation carriers. Standard management typically involves neoadjuvant chemotherapy followed by surgery and potenti...

Udobi(ME),Chinedu(SN),Afolabi(IS),Ezike(KN... Front Oncol None

...BRCA1 and BRCA2, alongside luminal regulators like GATA3, decline progressively with both advancing age and tumor aggres...

Gouveia(MC),Barroso-Sousa(R),Lapuchesky(L)... NPJ Breast Cancer 2026-03-03

...BRCA1/2 mutations, alongside a higher prevalence of impaired performance status. The pathologic complete response (pCR) ...

Haskoylu(S),Sahin(SB),Altıntas(A),Yildiz(S... Reprod Sci 2026-04-00

...BRCA1/2 mutations may already exhibit reduced ovarian reserve and are more vulnerable to gonadal damage, possibly due to...

D'Alonzo(M),Actis(S),Lavalle(G),Suraci(S),... Prenat Diagn 2026-04-00

The objective of this paper is to investigate the knowledge and attitudes of BRCA1/2 pathogenic variant carriers and gyn...

Scafetta(R),Troiano(R),Gullotta(C),Guarino... Eur J Cancer 2026-05-15

...BRCA1/2 mutation status. Among 1399 patients, 46 harbored germline BRCA1/2 mutations (13 BRCA1, 33 BRCA2), and 21 of the...

Kozak(VN),Oliveira(JC),Gradia(DF),Mathias(... Mol Diagn Ther 2026-07-00

...BRCA1, and BRCA2 and mismatch repair genes as the molecular explanations for familial clustering of specific cancer type...