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Decreased bone mineral density and content in neurofibromatosis type 1: lowest …

Kuorilehto(T),Pöyhönen(M),Bloigu(R),Heikkine… Osteoporos Int 2005-08-00

...NF1 patients. A total of 35 NF1 patients and 26 healthy controls were included in the present study. Of the participants...

Spectrum of single- and multiexon NF1 copy number changes in a cohort of 1,100 …

Wimmer(K),Yao(S),Claes(K),Kehrer-Sawatzki(H)… Genes Chromosomes Cancer 2006-03-00

...NF1), the most common tumor-predisposing disorder in humans, is caused by defects in the NF1 tumor-suppressor gene. Comp...

Local low-dose lovastatin delivery improves the bone-healing defect caused by N…

Wang(W),Nyman(JS),Moss(HE),Gutierrez(G),Mund… J Bone Miner Res 2010-07-00

...NF1), a disorder caused by mutations in the NF1 gene. To determine the contribution of NF1 in bone healing, we assessed ...

TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sh…

Park(GH),Lee(SJ),Yim(H),Han(JH),Kim(HJ),Sohn… Oncol Rep 2014-10-00

...NF1) caused by NF1 gene mutation is a commonly inherited autosomal dominant disorder. Malignant peripheral nerve sheath ...

NF1 exon 22 analysis of individuals with the clinical diagnosis of neurofibroma…

Muram-Zborovski(TM),Vaughn(CP),Viskochil(DH)… Am J Med Genet A 2010-08-00

...NF1). Most NF1 individuals develop age-related tumorigenic manifestations (e.g., neurofibromas), although individuals wi...

Monozygotic twins with neurofibromatosis type 1 (NF1) display differences in me…

Harder(A),Titze(S),Herbst(L),Harder(T),Guse(… Twin Res Hum Genet 2010-12-00

...NF1) is a common autosomal dominant disorder caused by heterozygotic inactivation of the NF1 tumor suppressor gene at 17...

Carboplatin induces optic nerve oligodendrocyte loss and impairs myelin sheath …

Aghoghovwia(BE),Ban(K),Stavropoulos(D),Chen(… Neuro Oncol 2026-07-21

...NF1)-associated optic pathway glioma (OPG). While carboplatin-containing chemotherapy is often first-line therapy for NF...

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions.

Silva(JM),Canche(L),Cheng(A),Young(LC),McCor… Proc Natl Acad Sci U S A 2026-06-02

...NF1 and SPRED1/2. Utilizing CRISPR-Cas9 methods to ablate NF1 or SPRED1/2 in isogenic "RASless" mouse embryonic fibrobla...

Assessment of Ecotropic Viral Integration Site 2B (EVI2B) Gene in Juvenile Myel…

Saharafi(P),Akar(İ),Ersoy-Evans(S),Anlar(B),… Biochem Genet 2024-04-00

...NF1 tumors. We analyzed DNA from 10, 20, and 3 patients with NF1, leukemia, and NF1-leukemia, respectively, and six NF1 ...

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neu…

Moutal(A),Yang(X),Li(W),Gilbraith(KB),Luo(S)… Pain 2017-12-00

...NF1) is a rare autosomal dominant disease linked to mutations of the Nf1 gene. Patients with NF1 commonly experience sev...

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