...BRCA1 which plays a multifunctional role in controlling genome integrity. Moreover, the most investigated DSBs enzyme in...
...BRCA1); and DNA-dependent serine/threonine protein kinase (DNA-PK)]; only rhein suppressed the expression of O(6)-methyl...
...BRCA1 and BRCA2 genes, whereas genetic testing for familial colorectal cancer is available from multiple laboratories. C...
BRCA1 and BRCA2 are tumor suppressor genes, familial mutations in which account for approximately 5% of breast cancer ca...
...BRCA1 related breast cancer.,A population of 68 BRCA1 related invasive breast cancers was evaluated for LVI by an experi...
...BRCA1/2 mutant-associated cancers. The ability of p53, wild-type and mutants, to transactivate from 11 human target REs ...
...BRCA1/2 mutation carriers.,Patients with BRCA1/2-mutated ovarian cancer were treated with olaparib within a dose-escalat...
To compare the frequency of visceral relapse of BRCA1/2-deficient ovarian cancer to that of nonhereditary controls.,All ...
...BRCA1, which encodes a ubiquitin ligase. How BRCA1 ligase activity was regulated following DNA damage was poorly underst...
...BRCA1 and BRCA2 deficient tumor cell lines. More recently, several small molecules targeting PARP-1 entered the clinic a...
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