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Evaluating women with ovarian cancer for BRCA1 and BRCA2 mutations: missed oppo…

Meyer(Larissa A),Anderson(Meaghan E),Lacour(… Obstet Gynecol 2010-05-18

To estimate the incidence of genetic counseling referral for ovarian cancer patients who are at substantial risk for a B...

Short-term surgical outcome and safety of risk reducing salpingo-oophorectomy i…

Kenkhuis(M J A),de Bock(G H),Elferink(P Oude… Maturitas 2010-12-10

Women with a BRCA1/2 mutation or members of a hereditary breast ovarian cancer family (HBOC) have an increased risk of d...

A BRCA1 promoter variant (rs11655505) and breast cancer risk.

Verderio(Paolo),Pizzamiglio(Sara),Southey(Me… J Med Genet 2010-07-28

...BRCA1 promoter (c.-2265C-->T) increases promoter activity and has a protective effect on breast cancer risk.,We genotype...

Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer:…

Pierce(Lori J),Phillips(Kelly-Anne),Griffith… Breast Cancer Res Treat 2010-08-20

...BRCA1/2 carriers. 655 women with BRCA1/2 mutations diagnosed with breast cancer and treated with BCT (n = 302) or M (n =...

Common variants associated with breast cancer in genome-wide association studie…

Wang(Xianshu),Pankratz(V Shane),Fredericksen… Hum Mol Genet 2010-09-28

...BRCA1 and BRCA2 carriers. Promising candidate SNPs from GWAS were identified as modifiers of breast cancer risk in BRCA1...

Candidate gene association studies: successes and failures.

Pasche(Boris),Yi(Nengjun) Curr Opin Genet Dev 2010-09-27

...BRCA1, BRAC2, MSH1, MLH2 and MSH6 only accounts for a small fraction of these cancers. Low to moderate penetrance tumor ...

Concomitant loss of heterozygosity at the BRCA1 and FHIT genes as a prognostic …

Silva Soares(Emerson Wander),de Lima Santos(… Cancer Genet Cytogenet 2010-05-04

...BRCA1 and FHIT genes in sporadic primary breast cancer. The aim of this study was to evaluate concomitant LOH at the BRC...

CCND1 and ZNF217 gene amplification is equally frequent in BRCA1 and BRCA2 asso…

Plevova(P),Cerna(D),Balcar(A),Foretova(L),Za… Neoplasma 2010-08-05

...BRCA1, 3 BRCA2, 2 non-BRCA). ZNF217 amplification was observed in three of 38 cases (8%; 2 BRCA1, 1 non-BRCA). There was...

Excretion of estrogens, catecholestrogens and phytoestrogens in carriers of BRC…

Berstein(L M),Koskela(A),Boyarkina(M P),Adle… Neoplasma 2010-08-05

BRCA1 gene mutation is associated with a combination of excessive aromatase activity/expression, predominantly estrogen ...

Targeting DNA repair in breast cancer: a clinical and translational update.

Amir(Eitan),Seruga(Bostjan),Serrano(Rosario)… Cancer Treat Rev 2010-11-02

...BRCA1 and BRCA2. Recent biologic findings suggest that in tumours in which one DNA repair pathway is deficient, concomit...

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