...BRCA1 and BRCA2 variants. RRSO has been shown to markedly reduce the risk of ovarian cancer and to confer a protective e...
...BRCA1 (BRCT domain), and docked favorably with DNA (PDB ID: 1TUP), demonstrating that DNA-binding capability remained in...
...BRCA1, BRCA2, and PALB2 variants, we delineated the genomic landscape of 96 MaBC cases. Subsequent whole-exome sequencin...
...BRCA1/2 and PALB2 mutation carriers had reduced PFS with first-line ET + CDK4/6i compared to wild-type patients.
...BRCA1-associated disease. The study by Moyer and colleagues demonstrated that RXR agonists, particularly IRX4204, delay ...
...BRCA1/2 mutation and/or genomic scar score (GSS) ≥45. Correlations with clinicopathological variables, histological subt...
...BRCA1 PV carriers, there is no evidence that BRCA1 and BRCA2 PV carriers have substantially increased risks of other non...
...BRCA1/2 or mismatch-repair genes, consistent with the fusion-negative UTROSCT subset (~30-45% of cases). At 20 months th...
...BRCA1 and RAD51, and accumulation of cytosolic DNA in S/G2-phase cells. These effects were independent of PARP1 but requ...
...BRCA1 and BRCA2 mutations, could reveal insights into both familial and non-familial causes of breast cancer. Australian...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
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