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TP53 BRCA1 CRISPR single-cell cancer

Li(Li),Halaby(Marie-Jo),Hakem(Anne),Cardoso(… J Exp Med 2010-06-08

...BRCA1, to sites of damage. Using mouse models for Rnf8 mutation, we report that Rnf8 deficiency leads to impaired sperma...

Gilbert(Penney M),Mouw(Janna K),Unger(Meredi… J Clin Invest 2010-05-20

...BRCA1. Indeed, ectopic expression of wild-type BRCA1 phenocopied the tumor suppressor function of HOXA9, and reducing BR...

Novello(A),Villar(S),Urioste(J) Cytogenet Genome Res 2010-06-14

...BRCA1 immunodetection we observed in early pachytene cells positive spots located over heterochromatic chromocenters tha...

El-Tanani(Mohamed K),Yuen(Hiu-Fung),Shi(Zhan… Cancer Sci 2010-09-14

...BRCA1 (Wt.BRCA1) and that a natural mutant allele of BRCA1 (Mut.BRCA1) diminished the effect of Wt.BRCA1 on OPN in vitro...

Rowling(Pamela J E),Cook(Rebecca),Itzhaki(La… J Biol Chem 2010-08-24

Carriers of germ line mutations in breast cancer susceptibility gene BRCA1 have an increased risk of developing breast a...

Fiorentino(Michelangelo),Judson(Gregory),Pen… Cancer Res 2010-04-28

BRCA1 functions as a tumor suppressor; recent work suggests that BRCA1 may also induce cell cycle arrest to allow for DN...

Takizawa(Yoshimasa),Qing(Yong),Takaku(Motoki… Nucleic Acids Res 2010-09-29

...BRCA1 and BRCA2. We found that human RAD51 directly binds GEMIN2/SIP1, a protein involved in spliceosome biogenesis. Bio...

Tinelli(Andrea),Malvasi(Antonio),Leo(Giusepp… Cancer Metastasis Rev 2010-08-13

...BRCA1) and BRCA2 genes mutations. The importance of recognizing the characteristics of hereditary ovarian cancer (HOC) a...

Antoniou(Antonis C),Chenevix-Trench(Georgia) Curr Opin Genet Dev 2010-09-27

...BRCA1 and BRCA2 mutation carriers presumably because BRCA1 breast cancer tumors are predominantly ER-negative and are bi...

Zhao(H),Logothetis(C J),Gorlov(I P) Prostate Cancer Prostatic Dis 2010-12-02

...BRCA1 gene pairs identified those patients with more than 99% specificity but relatively low sensitivity (approximately ...

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