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DNA methylome of familial breast cancer identifies distinct profiles defined by…

Flanagan(James M),Cocciardi(Sibylle),Waddell… Am J Hum Genet 2010-04-15

...BRCA1, BRCA2, and BRCAx) or intrinsic subtypes of breast cancer (basal, luminal A, luminal B, HER2-amplified, and normal...

Developmental arrest of Caenorhabditis elegans BRAP-2 mutant exposed to oxidati…

Koon(Janet C),Kubiseski(Terrance J) J Biol Chem 2010-05-27

...BRCA1-associated protein 2 (BRAP-2). A mutant containing a deletion of brap-2 was highly sensitive to oxidizing conditio...

Cross-talk between non-genomic and genomic signalling pathways--distinct effect…

Silva(Elisabete),Kabil(Alena),Kortenkamp(And… Toxicol Appl Pharmacol 2010-06-11

...BRCA1 and CCND1, and the proliferation of breast cancer cells. Despite commonalities in their estrogenicity as judged by...

Male breast cancer.

Gómez-Raposo(César),Zambrana Tévar(Francisco… Cancer Treat Rev 2010-09-28

...BRCA1 mutations. Klinefelter syndrome is the strongest risk factor for developing male breast carcinoma. Men tend to be ...

Transcriptional regulation of the base excision repair pathway by BRCA1.

Saha(Tapas),Rih(Jeong Keun),Roy(Rabindra),Ba… J Biol Chem 2010-07-21

...BRCA1 induces antioxidant-response gene expression and protects cells against oxidative stress. We now report that BRCA1...

BRCA1/2 predictive testing and gender: uptake, motivation and psychological cha…

Denayer(L),Boogaerts(A),Philippe(K),Legius(E… Genet Couns 2010-03-18

BRCA1/2 predictive testing and gender: Uptake, motivation and psychological characteristics: Data on male uptake of BRCA...

Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on st…

Asakawa(Hideki),Koizumi(Hirotaka),Koike(Ayak… Breast Cancer Res 2010-09-15

...BRCA1 foci were observed before treatment in the majority of the cases and only decreased after EC in thirteen cases. Th...

Increased chromosomal radiosensitivity in women carrying BRCA1/BRCA2 mutations …

Ernestos(Beroukas),Nikolaos(Pandis),Koulis(G… Int J Radiat Oncol Biol Phys 2010-03-31

Several in vitro studies suggest that BRCA1 and BRCA2 mutation carriers present increased sensitivity to ionizing radiat...

[Penetrance of BRCA1 gene mutation and DNA mitochondrial in Tunisian breast can…

Troudi(Wafa),Loueslati(Besma),Baccar(Amal),B… Tunis Med 2010-03-23

The aim of this study is to evaluate the implication of BRCA1 gene and the mitochondrial micro satellite (situated betwe...

ATM modulates transcription in response to histone deacetylase inhibition as pa…

Jang(Eun Ryoung),Choi(Jae Duk),Park(Mi Ae),J… Exp Mol Med 2010-09-27

...BRCA1- dependent manner, respectively. These findings suggest that ATM and its kinase activity are essential for the TSA...

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