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[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BR…

Magnowski(Piotr),Seremak-Mrozikiewicz(Agnies… Ginekol Pol 2010-10-22

...BRCA1 gene, and genotype frequency within 677C>T MTHFR polymorphism, were identified. The analysis of genotype frequency...

Induction of breast cancer in wild type p53 cells by BRCA1-IRIS overexpression.

Elshamy(Wael M) Hawaii Med J 2010-10-21

...BRCA1-IRIS triggers WIP1 expression in p53-dependent and -independent manner. BRCA1-IRIS triggers the expression and cyt...

Frequent mutation of BAP1 in metastasizing uveal melanomas.

Harbour(J William),Onken(Michael D),Roberson… Science 2010-12-28

...BRCA1-associated protein 1 (BAP1) on chromosome 3p21.1 in 26 of 31 (84%) metastasizing tumors, including 15 mutations ca...

Distinctive DNA methylation patterns of cell-free plasma DNA in women with mali…

Liggett(Thomas E),Melnikov(Anatoliy),Yi(Qilo… Gynecol Oncol 2010-12-23

...BRCA1, CALCA, and CDKN1C) were informative for differentiating between BOD vs. HC, with a sensitivity of 90.0% and a spe...

Cisplatin affects the conformation of apo form, not holo form, of BRCA1 RING fi…

Atipairin(Apichart),Canyuk(Bhutorn),Ratanaph… Chem Biodivers 2010-12-30

...BRCA1 in cancer cells leads to chemosensitivity. Approaching the BRCA1 RING protein as a potentially molecular target fo...

Novel BRCA1/2 mutations in Serbian breast and breast-ovarian cancer patients wi…

Dobricić(Jelena),Branković-Magić(Mirjana),Fi… Cancer Genet Cytogenet 2010-09-23

...BRCA1/2 genes in a Serbian population. Using automated DNA sequencing, we tested individuals for BRCA mutations, based o...

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors a…

Molyneux(Gemma),Geyer(Felipe C),Magnay(Fiona… Cell Stem Cell 2010-12-22

...Brca1 in mouse mammary epithelial luminal progenitors produces tumors that phenocopy human BRCA1 breast cancers. They al...

Non-founder BRCA1 mutations in Russian breast cancer patients.

Iyevleva(Aglaya G),Suspitsin(Evgeny N),Kroez… Cancer Lett 2010-11-26

...BRCA1 heterozygotes, which carried BRCA1 deletions involving exons 1-2 and 3-7, respectively. Based on the results of th...

Synergistic chemosensitivity of triple-negative breast cancer cell lines to pol…

Hastak(Kedar),Alli(Elizabeth),Ford(James M) Cancer Res 2010-11-23

...BRCA1-associated breast cancers. BRCA1-mutant cells exhibit sensitivity to gemcitabine, cisplatin, and poly(ADP-ribose) ...

Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependen…

Koike(Ayaka),Nishikawa(Hiroyuki),Wu(Wenwen),… Cancer Res 2010-10-07

...BRCA1 or its partner, RAP80, enhanced IR-induced NPM1 foci and prolonged persistence of the foci, possibly implicating B...

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