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Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA…

De Brakeleer(Sylvia),De Grève(Jacques),Loris… Hum Mutat 2010-10-29

...BRCA1 and BRCA2 were reported as high penetrant breast cancer predisposing genes. However, mutations in these genes are ...

Attitudes and practice of genetic counselors regarding anonymous testing for BR…

Ader(Tammy),Susswein(Lisa R),Callanan(Nancy … J Genet Couns 2010-04-15

...BRCA1/2, genetic counselors were invited to complete an internet-based survey via the NSGC Familial Cancer Risk Counseli...

Selecting for BRCA1 testing using a combination of homogeneous selection criter…

Miolo(GianMaria),Canzonieri(Vincenzo),De Gia… BMC Cancer 2010-01-13

BRCA1 gene-related tumours are more frequently estrogen receptor (ER) and progesterone receptor (PR) negative with a low...

Impaired DNA damage response--an Achilles' heel sensitizing cancer to chemother…

Darzynkiewicz(Zbigniew),Traganos(Frank),Wlod… Eur J Pharmacol 2010-01-25

...BRCA1 and BRCA2 are particularly sensitive to combined treatment with DNA damaging drugs and inhibitors of poly(ADP-ribo...

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, …

Arnold(Jeremy M),Choong(David Y H),Thompson(… Breast Cancer Res Treat 2010-03-10

...BRCA1/2 cases in which the frequency was 22%. In contrast, we found mutations of GATA-3 in only 4% of 81 sporadic tumors...

Health behaviors among Ashkenazi Jewish individuals receiving counseling for BR…

Quach(Jackie),Porter(Kyle),Leventhal(Howard)… Fam Cancer 2010-01-18

Little of the research involving individuals undergoing testing for BRCA1/2 mutations has examined the effect of genetic...

The BRCA Self-Concept Scale: a new instrument to measure self-concept in BRCA1/…

Esplen(Mary Jane),Stuckless(Noreen),Hunter(J… Psychooncology 2010-01-15

Genetic testing for BRCA1/2 has psychosocial impacts including those related to views of personal health, sense of self ...

Genetic sequence variations of BRCA1-interacting genes AURKA, BAP1, BARD1 and D…

Guénard(Frédéric),Labrie(Yvan),Ouellette(Gen… J Hum Genet 2010-02-16

...BRCA1 and BRCA2 and the implication of these genes in many key cellular processes, assessment of genes encoding BRCA1-in...

Fertility in women with BRCA mutations: a case-control study.

Pal(Tuya),Keefe(David),Sun(Ping),Narod(Steve… Fertil Steril 2010-04-16

...BRCA1 and BRCA2), compared with noncarrier family members.,Matched case-control study.,Academic.,A total of 2,254 BRCA c...

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination dur…

Xu(Ye),Sun(Yingli),Jiang(Xiaofeng),Ayrapetov… J Cell Biol 2010-11-10

...brca1 and 53BP1 to DSBs. These results identify p400 as a novel DNA damage response protein and demonstrate that p400-me...

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