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Increased cancer risks for relatives of very early-onset breast cancer cases wi…

Dite(G S),Whittemore(A S),Knight(J A),John(E… Br J Cancer 2010-10-25

...BRCA1 and BRCA2, respectively. The ovarian cancer SIR was 12.38 (3.1-49.51) for BRCA1 and the prostate cancer SIR was 18...

BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic br…

Kluk(Brian J),Fu(Yebo),Formolo(Trina A),Zhan… Int J Biol Sci 2010-12-10

...BRCA1 is a well-known player in the etiology of breast cancer. While familial breast cancer is often marked by BRCA1 mut...

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian…

Hansen(Thomas v O),Jønson(Lars),Albrechtsen(… Breast Cancer Res Treat 2009-07-29

...BRCA1 exon 5-7 deletion with a novel breakpoint, a BRCA1 exon 13 duplication, a BRCA1 exon 17-19 deletion, a BRCA1 exon ...

Differences and similarities in breast cancer risk assessment models in clinica…

Jacobi(Catharina E),de Bock(Geertruida H),Si… Breast Cancer Res Treat 2009-07-29

...BRCA1/2-negative or untested families. After a systematic literature search seven models were selected: Gail-2, Claus Mo...

Prepubertal physical activity up-regulates estrogen receptor beta, BRCA1 and p5…

Wang(M),Yu(B),Westerlind(K),Strange(R),Khan(… Breast Cancer Res Treat 2009-09-30

Findings in BRCA1 mutation carriers suggest that physical activity, particularly during childhood, may be linked to a re...

BRCA1 promoter methylation is associated with increased mortality among women w…

Xu(Xinran),Gammon(Marilie D),Zhang(Yujing),B… Breast Cancer Res Treat 2009-07-29

...BRCA1 in the breast where somatic mutations of BRCA1 are rare. To better understand breast cancer etiology and progressi...

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA…

Rebbeck(Timothy R),Antoniou(Antonis C),Llopi… Breast Cancer Res Treat 2009-09-30

...BRCA1 or BRCA2 mutation carriers, we undertook a multi-center study of 3,442 BRCA1 and 2,095 BRCA2 mutation carriers.,We...

No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 …

Spurdle(Amanda B),Deans(Andrew J),Duffy(Davi… Breast Cancer Res Treat 2009-07-29

...BRCA1 and BRCA2 carriers (adjusted hazard ratio (HR) 0.72 (95% CI = 0.53-0.99; P = 0.04 for BRCA1, HR 1.47 (95% CI = 0.9...

Tumor size is an unreliable predictor of prognosis in basal-like breast cancers…

Foulkes(William D),Grainge(Matthew J),Rakha(… Breast Cancer Res Treat 2009-11-17

...BRCA1-related breast cancers. We hypothesized that the rule also might not apply in basal-like breast cancers (BLBC), an...

Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical…

Thirthagiri(E),Lee(S Y),Kang(P),Lee(D S),Toh… Breast Cancer Res 2009-04-24

...BRCA1 and 31 in BRCA2). Notably, many mutations are novel (13 of the 30 BRCA1 mutations and 24 of the 44 BRCA2). We repo...

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