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Advantages of the high resolution melting in the detection of BRCA1 or BRCA2 mu…

Jiménez(Inmaculada de Juan),Esteban Cardeños… Clin Biochem 2009-12-29

...BRCA1/BRCA2 mutation carriers among the family members of index patient (IP) and for distinguishing the presence of two ...

Therapeutic options for triple-negative breast cancers with defective homologou…

Jaspers(Janneke E),Rottenberg(Sven),Jonkers(… Biochim Biophys Acta 2009-11-03

...BRCA1-deficient cells. Here, we review the features shared between triple-negative, basal-like and BRCA1-related breast ...

A role of BRCA1 and BRCA2 germline mutations in breast cancer susceptibility wi…

Palomba(Grazia),Loi(Angela),Uras(Antonella),… BMC Cancer 2009-12-11

...BRCA1-2 mutations by DHPLC analysis and DNA sequencing. Association of BRCA1 and BRCA2 mutational status with clinical a...

Elevated level of 8-oxo-7,8-dihydro-2'-deoxyguanosine in leukocytes of BRCA1 mu…

Dziaman(Tomasz),Huzarski(Tomasz),Gackowski(D… Int J Cancer 2009-09-15

Carriers of BRCA1 mutation face highly increased risk of breast and ovarian cancer and some studies with cell culture su...

Triple-negative breast cancer: novel therapies and new directions.

Pal(Sumanta Kumar),Mortimer(Joanne) Maturitas 2009-11-05

...BRCA1-positive breast cancer. In recent years, a greater understanding of the biology of this disease has led to the dev...

The trouble with sliding windows and the selective pressure in BRCA1.

Schmid(Karl),Yang(Ziheng) PLoS One 2009-02-04

...BRCA1 gene experienced a synonymous rate reduction driven by purifying selection is likely an artifact of the sliding wi...

Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast.

Malone(J L),Nelson(A C),Lieberman(R),Anderso… J Pathol 2009-02-20

...BRCA1 hereditary cancers, which are usually ER(-). We studied BRCA2 protein expression and S3291 phosphorylation in norm...

[Knockout mice in the service of reproduction].

Escalier(D) Gynecol Obstet Fertil 2009-02-10

...Brca1), primordial follicles (Lhx8), granulosa cells (Lrh1), and, for both sexes, mitochondria (Immp2l) and meiosis (Ubb...

What is triple-negative breast cancer?

Irvin(William J),Carey(Lisa A) Eur J Cancer 2009-01-22

...BRCA1 mutation carriers, in young women and in African-American women. The reasons for these associations are unclear bu...

Histone ubiquitination associates with BRCA1-dependent DNA damage response.

Wu(Jiaxue),Huen(Michael S Y),Lu(Lin-Yu),Ye(L… Mol Cell Biol 2009-02-04

...BRCA1, recognizes ubiquitinated histones H2A and H2B. The interaction between RAP80 and ubiquitinated histones H2A and H...

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