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Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.

Stansfield(BK),Bessler(WK),Mali(R),Mund(JA),… Am J Pathol 2014-01-00

...NF1) results from mutations in the NF1 tumor-suppressor gene, which encodes neurofibromin, a negative regulator of diver...

Paired associate learning in children with neurofibromatosis type 1: implicatio…

Payne(JM),Barton(B),Shores(EA),North(KN) J Neurol 2013-01-00

...Nf1 (+/-) mice and children with NF1 using a well-validated measure of visuospatial learning. Children with NF1 (n = 71)...

Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370…

García-Ortí(L),Cristóbal(I),Cirauqui(C),Guru… PLoS One 2012-00-00

...NF1 locus were identified as alternative mechanisms to downregulate NF1. NF1 downregulation is a common event in AML, an...

Neurofibromatosis type 1 tumour suppressor gene expression is deficient in psor…

Karvonen(SL),Koivunen(J),Nissinen(M),Ylä-Out… Br J Dermatol 2004-02-00

...NF1) protein (neurofibromin) accelerates the inactivation of Ras-GTP in various cell types. Somatic mutations of the NF1...

Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine amin…

Dasgupta(B),Yi(Y),Hegedus(B),Weber(JD),Gutma… Cancer Res 2005-11-01

...Nf1-/- astrocyte growth advantage. Moreover, Nf1-deficient astrocytes exhibit increased protein translation. As part of ...

Clinical features of 58 Japanese patients with mosaic neurofibromatosis 1.

Tanito(K),Ota(A),Kamide(R),Nakagawa(H),Niimu… J Dermatol 2014-08-00

...NF1" is generally assumed to be the result of somatic mosaicism for a NF1 mutation, and patients with mosaic NF1 have ty...

Fractures in children with neurofibromatosis type 1 from two NF clinics.

George-Abraham(JK),Martin(LJ),Kalkwarf(HJ),R… Am J Med Genet A 2013-05-00

...NF1, ages 5-20 years, using a standardized questionnaire. We surveyed 256 individuals with NF1 from two multidisciplinar...

Motor deficits in neurofibromatosis type 1 mice: the role of the cerebellum.

van der Vaart(T),van Woerden(GM),Elgersma(Y)… Genes Brain Behav 2011-06-00

...NF1. Using the Rotarod, a non-specific motor performance test, we confirmed that, like NF1 patients, Nf1(+/-) mice have ...

Neurofibromatosis from Head to Toe: What the Radiologist Needs to Know.

Wang(MX),Dillman(JR),Guccione(J),Habiba(A),M… Radiographics 2022-00-00

...NF1 and NF2 tumor suppressor genes, respectively. Although they share a common name, NF1 and NF2 are distinct disorders ...

Neurofibromatosis Type 1 Patients With Epilepsy: A Comprehensive Analysis of De…

Kodali(N),Terrany(A),Kumar(KD),Chambers(S),A… Exp Dermatol 2024-11-00

...NF1) is the most common neurocutaneous disorder in the United States. Due to a nonfunctional mutation in the NF1 gene, t...

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