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Analysis of a set of missense, frameshift, and in-frame deletion variants of BR…

Carvalho(Marcelo),Pino(Maria A),Karchin(Rach… Mutat Res 2009-03-24

...BRCA1 are responsible for breast and ovarian cancer susceptibility. One possible outcome of genetic testing for BRCA1 is...

Expression profile of BRCA1 and BRCA2 genes in premenopausal Mexican women with…

Loredo-Pozos(Gloria),Chiquete(Erwin),Oceguer… Med Oncol 2009-11-25

...BRCA1 expression than older women (P < 0.05). BRCA1 and BRCA2 expression correlated in healthy, but not in tumor tissues...

Uptake of clinical genetic testing for ovarian cancer in Ontario: a population-…

Metcalfe(Kelly A),Fan(Isabel),McLaughlin(Joh… Gynecol Oncol 2009-01-02

...BRCA1 or BRCA2. In 2001, genetic testing for BRCA1 and BRCA2 became freely available to all women in Ontario with a diag...

Hereditary breast cancer syndromes and clinical implications.

Majdak-Paredes(E J),Fatah(F) J Plast Reconstr Aesthet Surg 2009-03-04

...BRCA1/2 genes and the high-risk patients for developing breast cancer would allow a better understanding of the natural ...

Growth and molecular interactions of the anti-EGFR antibody cetuximab and the D…

Oliveras-Ferraros(Cristina),Vazquez-Martin(A… Int J Oncol 2009-02-02

...BRCA1. Concurrent treatment with sub-optimal doses of cetuximab significantly enhanced CDDP-induced apoptotic cell death...

Can genetic testing guide treatment in breast cancer?

Tutt(Andrew),Ashworth(Alan) Eur J Cancer 2009-01-22

...BRCA1 or BRCA2 mutation? In this review, we consider whether BRCA1 or BRCA2 mutation influences the choice of breast scr...

The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.

Ghosh(Agnidipta),Shuman(Stewart),Lima(Christ… Mol Cell 2009-01-15

...BRCA1 C-terminal (BRCT) domain. The structure and mutational analysis reveals that Fcp1 and Scp1 (a Ser5-selective phosp...

Histone ubiquitination associates with BRCA1-dependent DNA damage response.

Wu(Jiaxue),Huen(Michael S Y),Lu(Lin-Yu),Ye(L… Mol Cell Biol 2009-02-04

...BRCA1, recognizes ubiquitinated histones H2A and H2B. The interaction between RAP80 and ubiquitinated histones H2A and H...

Absence of germline BRCA1 mutations in familial pancreatic cancer patients.

Axilbund(Jennifer E),Argani(Pedram),Kamiyama… Cancer Biol Ther 2009-06-15

...BRCA1 gene may confer an increased risk of developing pancreatic cancer. To determine if BRCA1 mutations explain a signi...

Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients tr…

Kim(Hong-Tae),Lee(Jong-Eun),Shin(Eun-Soon),Y… J Clin Oncol 2009-01-13

To determine whether germ-line variations in BRCA1 affect outcome in non-small-cell lung cancer (NSCLC) patients treated...

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