...BRCA1 and 31 in BRCA2). Notably, many mutations are novel (13 of the 30 BRCA1 mutations and 24 of the 44 BRCA2). We repo...
...BRCA1/BRCA2 mutations, were genotyped for major gene rearrangements in BRCA1/BRCA2 using Multiplex ligation-dependent pr...
Mutations in PIK3CA and alterations of BRCA1 expression are common in breast cancer and have been correlated with altere...
...BRCA1/BRCA2 mutations were identified in ten MBCs, in particular, two cases (1.9%) carried BRCA1 and eight cases (7.4%) ...
...BRCA1 expression (P = 0.001). Breast tumors (n = 3) from patients with a proven BRCA1 germline mutation also showed a si...
...BRCA1 nuclear-cytoplasmic shuttling.,Cytoplasmic relocalization of the BRCA1 protein may be a mechanism whereby the BRCA...
...BRCA1 or BRCA2 confer increased lifetime risk for ovarian, fallopian tube, and primary peritoneal carcinoma. This risk c...
...BRCA1 inherited cancers, but does not correlate with clinical outcome. These very interesting findings caution that the ...
...BRCA1 and BRCA2, sister chromatid exchange, and endometrial thickness were also evaluated. Lumbar spine and femoral neck...
...BRCA1) using multiplex PCR for the detection of allelic imbalances. Most of the investigated FEAs showed a lower frequen...
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