...BRCA1/BRCA2 PGV carriers (915 BRCA1, 901 BRCA2); and (2) age-matched noncarriers for a familial PGV (727 BRCA1 and 520 B...
...BRCA1/2 mutations. However, their clinical utility is mainly restricted to HRD tumors and also hindered by innate or acq...
...BRCA1 and ATM recruitment to γH2AX foci in an acetylation-dependent manner. Moreover, FASN inhibition-mediated DNA repai...
...BRCA1, and RAD51 - significantly enriched in the HR pathway. Molecular docking and dynamic simulations indicate that RSV...
...BRCA1/2 status, largely due to not knowing what BRCA1/2 was. While 52% perceived prostate cancer as a high-risk conditio...
...BRCA1 and CASP8 mutations, while copy number alterations in FGF4, FGF19 and CCND1 increased progressively with age. CONC...
...BRCA1/2 (n = 47) and triple-negative (n = 17) patients than in paired controls. IGHM and CD5L were also lower in BRCA1/2...
...BRCA1/2 mutations, this perspective argues for a fundamental shift in national health policy. We propose that the curren...
...BRCA1/2 mutations both significantly improved DFS (p<0.05). Multivariate analysis confirmed TNBC, positive lymph node me...
...BRCA1-deficient cell lines (SUM149PT, MDA-MB-436, and HCC1937) and the BRCA2-deficient cell line (Capan-1). Mechanistic ...
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