Blondot(Marie-Lise),Dragin(Loic),Lahouassa(H… Retrovirology 2015-10-12

...SLX4 endonuclease complex and how Vpr-induced inappropriate activation of this complex leads to G2 arrest. Here, we will...

Saint-Léger(Adélaïde),Koelblen(Melanie),Civi… Cell Cycle 2015-08-13

...SLX4 as well as GEN1 and MUS81, 2 different types of endonucleases with resolvase activities. We propose that various ty...

García-Luis(Jonay),Machín(Félix) Nat Commun 2015-10-26

...Slx4, are also essential to prevent the formation of spontaneous SCBs that depend on the homologous recombination pathwa...

Lachaud(Christophe),Castor(Dennis),Hain(Karo… J Cell Sci 2015-04-17

...SLX4 is recruited to sites of ICL induction but that the UBZ-deleted form of SLX4 in cells from FA patients is not. SLX4...

Leung(Grace P),Aristizabal(Maria J),Krogan(N… G3 (Bethesda) 2015-01-23

...SLX4 or HRQ1, suggesting that Rtt107 has an important role in response to this type of DNA lesion. Although RTT107 and S...

Sarbajna(Shriparna),West(Stephen C) Trends Biochem Sci 2015-04-06

...SLX4-MUS81-EME1) complex, and the GEN1 resolvase. Recent studies have linked the deficiency of one or more of these enzy...

Kim(Yonghwan) Mol Cells 2015-06-02

...SLX4 is emphasized by the identification of causative mutations of SLX4 genes in patients diagnosed with Fanconi anemia ...

Berger(Gregory),Lawrence(Madeleine),Hué(Step… J Virol 2015-03-16

...SLX4 (huSLX4) and could be abolished by small interfering RNA (siRNA) depletion of any member of the SLX4 complex. In co...

Nair(Nidhi),Castor(Dennis),Macartney(Thomas)… DNA Repair (Amst) 2015-10-19

...SLX4 scaffold protein, which is itself instrumental for ICL repair. It was previously reported that mutations in SLX4 th...

Sarangi(Prabha),Altmannova(Veronika),Holland… Cell Rep 2015-07-09

...Slx4, and this SUMO-mediated role is genetically separable from two main UV lesion repair processes. These effects of Sa...