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Spatio-Temporal Gene Expression Profiling during In Vivo Early Ovarian Follicul…

Bonnet(Agnes),Servin(Bertrand),Mulsant(Phili… PLoS One 2016-06-21

...SPO11 meiotic protein covalently bound to DSB (SPO11), bone morphogenetic protein 15 (BMP15) and WEE1 homolog 2 (S. pomb...

INTER- AND INTRASPECIFIC RELATIONSHIPS BETWEEN NUCLEAR DNA CONTENT AND CELL SIZ…

Von Dassow(Peter),Petersen(Timothy W),Chepur… J Phycol 2016-04-05

...Spo11/TopVIA genes were selected for quantitative PCR estimation of haploid genome size in subclones of selected T. weis...

SPO11-C631T Gene Polymorphism: Association With Male Infertility and an in Sili…

Karimian(Mohammad),Nikzad(Hossein),Azami-Tam… J Family Reprod Health 2016-04-06

...SPO11 gene with male infertilityfollowed by an in silico approach. SPO11 is a gene involved in meiosis and spermatogenes...

A DNA topoisomerase VI-like complex initiates meiotic recombination.

Vrielynck(Nathalie),Chambon(Aurélie),Vezon(D… Science 2016-03-14

...SPO11-1 and SPO11-2) and is absolutely required for the formation of the SPO11-1/SPO11-2 heterodimer. These findings sug...

The TopoVIB-Like protein family is required for meiotic DNA double-strand break…

Robert(T),Nore(A),Brun(C),Maffre(C),Crimi(B)… Science 2016-03-14

...SPO11 and is required for meiotic DSB formation. We conclude that meiotic DSBs are catalyzed by a complex involving SPO1...

High throughput sequencing reveals alterations in the recombination signatures …

Rockmill(Beth),Lefrançois(Philippe),Voelkel-… PLoS Genet 2015-02-19

Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs)...

ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicat…

Blitzblau(Hannah G),Hochwagen(Andreas) Elife 2015-07-16

...Spo11 nuclease. Without this checkpoint, cells formed DSBs on partially replicated chromosomes. Importantly, such DSBs f...

Spp1 at the crossroads of H3K4me3 regulation and meiotic recombination.

Acquaviva(Laurent),Drogat(Julie),Dehé(Pierre… Epigenetics 2015-05-11

...Spo11 was uncovered only recently. The PHD-containing subunit Spp1, by interacting with H3K4me3 and Mer2, was shown to p...

Synthetic viability genomic screening defines Sae2 function in DNA repair.

Puddu(Fabio),Oelschlaegel(Tobias),Guerini(Il… EMBO J 2015-08-12

...Spo11 from DSB termini, allowing resection and HR to ensue. Mitotic roles of Sae2 and Mre11 nuclease have remained enigm...

Two separable functions of Ctp1 in the early steps of meiotic DNA double-strand…

Ma(Lijuan),Milman(Neta),Nambiar(Mridula),Smi… Nucleic Acids Res 2015-12-15

...Spo11-oligonucleotide complexes from 5' ends (clipping) and their resection to generate invasive 3'-end single-stranded ...

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