...BRCA1 testing acceptance in one large kindred. We also present data on baseline access to genetic information as well as...
...BRCA1/2 mutant.,One hundred and fourteen BRCA1/2 -negative hereditary breast cancer patients from independent families a...
...BRCA1 or BRCA2. Functionally, CIP2A depletion was shown to inhibit the expression of its target protein c-Myc. Loss of C...
...BRCA1-containing foci. Mutation of BRCA1 at S1497 and S1189/S1191 resulted in loss of cdk1-mediated phosphorylation and ...
...BRCA1-positive breast cancer. In recent years, a greater understanding of the biology of this disease has led to the dev...
...BRCA1, BRCA2, MLH1, MSH2, APC or TP53 genes did not detect a pathogenic germline mutation. Heteroduplex analysis and dir...
...BRCA1 mutation carriers contains expanded luminal progenitor cells, suggesting a broader role for BRCA1 in mammary devel...
...BRCA1/2 testing) who completed the GCSS following pretest counseling. The results suggest that the GCSS was reliable (Cr...
...BRCA1), 17 beta hydroxy steroid dehydrogenase type 1 (HSD17B1) and type 2 (HSD17B2). Restriction enzyme based Methylatio...
BRCA1 and BRCA2 germ-line mutations occur in a significant number of unselected ovarian cancer (OC) patients, thus makin...
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