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Prostate screening uptake in Australian BRCA1 and BRCA2 carriers.

McKinley(Joanne M),Weideman(Prue C),Jenkins(… Hered Cancer Clin Pract 2009-12-29

Men who carry mutations in BRCA1 or BRCA2 are at increased risk for prostate cancer. However the efficacy of prostate sc...

Selected aspects of inherited susceptibility to prostate cancer and tumours of …

Cybulski(Cezary) Hered Cancer Clin Pract 2009-12-29

...BRCA1, CHEK2 and NBS1 confer an increased prostate cancer risk in Polish men. We provide evidence that CHEK2 is a multi-...

BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis t…

Yan(M),Rayoo(M),Takano(E A),Thorne(H),,Fox(S… Br J Cancer 2009-10-14

...BRCA1, BRCA2 and BRCAX breast cancers.,Immunoperoxidase staining for HIF-1alpha, PHD1, PHD2, PHD3, VEGF and FIH was carr...

Dynamic interactions of proteins in complex networks: identifying the complete …

Christensen(Devin E),Klevit(Rachel E) FEBS J 2009-10-22

...BRCA1/BARD1 can interact with 10 different E2s. The ability of BRCA1 to interact with multiple E2s is likely to be a com...

A selective requirement for 53BP1 in the biological response to genomic instabi…

Cao(Liu),Xu(Xioaling),Bunting(Samuel F),Liu(… Mol Cell 2009-09-10

...Brca1 (Brca1(Delta 11/Delta 11)), we show that deletion of p53 binding protein 1 (53BP1) selectivity abrogates senescenc...

Human papillomaviruses activate the ATM DNA damage pathway for viral genome amp…

Moody(Cary A),Laimins(Laimonis A) PLoS Pathog 2009-12-16

...BRCA1 and NBS1. This activation is necessary for viral genome amplification, as well as for formation of viral replicati...

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF…

Machida(Yuichi J),Machida(Yuka),Vashisht(Aja… J Biol Chem 2009-12-22

...BRCA1-associated protein 1 (BAP1) possesses growth inhibitory activity and functions as a tumor suppressor. In this stud...

A role for BRCA1 in uterine leiomyosarcoma.

Xing(Deyin),Scangas(George),Nitta(Mai),He(Le… Cancer Res 2009-11-23

...BRCA1 protein is absent in 29% of human ULMS and that BRCA1 promoter methylation is the likely mechanism of BRCA1 downre...

Smad4 loss in mice causes spontaneous head and neck cancer with increased genom…

Bornstein(Sophia),White(Ruth),Malkoski(Steph… J Clin Invest 2009-11-17

...Brca1 and Rad51 proteins in human HNSCC. In addition to the above changes in tumor epithelia, both normal head and neck ...

Impact of androgen receptor cytosine-adenine-guanine polymorphisms on clinical …

Li(Andrew J),McAllister(Paula),Karlan(Beth Y) Gynecol Oncol 2009-12-11

...BRCA1/2 mutation positive women with ovarian cancer.,We identified BRCA1/2 ovarian cancer patients with banked serum fro...

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