...Brca1. Although both lesions are processed by independent repair pathways and trigger signaling responses by distinct ki...
...BRCA1 germline mutation.,This study reveals the molecular complexity of BRCA1 breast tumours, which are found to display...
...BRCA1 phosphorylation at the damage site. However, recruitment of ATR checkpoint kinase to the damage site was not affec...
...BRCA1/2 and TP53 status and overall survival (OS) were determined. Thirty-eight had a short platinum-free interval (PFI;...
...BRCA1/2 carriers and women with unknown mutation statuses. Women who had cancer (32%), however, showed clinically signif...
...BRCA1 (NBR1) is a highly conserved multidomain protein that interacts and colocalizes with Spred2 in vivo. Attenuation o...
...BRCA1 or BRCA2 mutations. Members of families with BRCA1 mutations had a 1.6-fold (95% CI, 1.2-fold to 2.3-fold) higher ...
...BRCA1/BRCA1-associated RING domain protein (BARD1) complex. Knocking down of UBE2T expression with small interfering RNA...
...BRCA1 and BRCA2 but with a stronger association to BRCA1 in malignant cases. Both BRCA1 and BRCA2 showed odds ratios of ...
Germline mutations in the BRCA1 and BRCA2 genes predispose to breast and ovarian cancer. A variable incidence of mutatio...
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